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Synthesis
… support researchers exploring how to convert sequence into functional assessments. This is done by synthesizing genes, … and assembling physical DNA constructs that can then be functionally characterized.    We provide custom DNA …
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How to Target a Microbial Needle within a Community Haystack
… cycles remains unexplored and uncultivated. Developing a more targeted genomic approach would allow researchers to focus on specific microbes within metagenome samples and associate their sequences with their roles within their environments. Summary The traditional shotgun …
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Taking Stock of the Known and Unknown Microbial Space
Metagenomic datasets could help map out microbial diversity hotspots Over the past few decades, advancements … said co-first author Dongying Wu, a member of the Functional Annotation team within the JGI’s Microbiome Data … “It’s a reminder of the urgency to cultivate new microbial species.” Targeted Explorations for Understanding the …
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Extensive Genetic Diversity is Present within North American Switchgrass Germplasm
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Workforce Development & Education Outreach
… foster a profound understanding of research methodologies within the realm of education. … Through the Berkeley Lab …
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Natural Variation in the Multidrug Efflux Pump SGE1 Underlies Ionic Liquid Tolerance in Yeast
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Enlarging Windows into Understanding Gene Functions
… the binding location for most transcription factors in a species,” O’Malley said. “It’s a unique capability; no one … which allows researchers to conduct comparative analyses across the genomes of multiple species in a single … there is no shortage of fungal genomes anymore, but their functional interpretation is as tough as it has been 10 …
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Tracing the Evolution of Shiitake Mushrooms
New genomes highlight the diversity of white rot fungi in the genus Lentinula   The … from the Americas to trace the evolution of Lentinula species.The Lentinula genus diverged roughly 28 million … potential conservation threat for wild species. Sequencing across genomes also provided an opportunity to assess …
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Comparative Analysis of 126 Cyanobacterial Genomes Reveals Evidence of Functional Diversity Among Homologs of the Redox-Regulated CP12 Protein    
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A Grass Model to Help Improve Giant Miscanthus
National Laboratory (Berkeley Lab), and collaborators across Europe and Asia. CABBI partners include the University … M. sinensis and a tetraploid M. sacchariflorus , another species of Miscanthus that was sequenced. Understanding the … wild Miscanthus lineages to better understand the genetic diversity of the grass, which could help in optimizing …
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Evolution of a Fungal Gene Expression Regulator
… reported on the largest analysis of 5mC distribution across the fungal tree of life to date, involving more than 500 species of fungi. The Impact Interactions between plants and … User Facility, and others like it, are uncovering the true diversity of the fungal kingdom. The abundance of fungal …
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An expanded evaluation of protein function prediction methods shows an improvement in accuracy
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