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Biodesign
… to convert sequence into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes … automations for DNA design, assembly and analysis Overview of biodesign products The JGI Biodesign platform enables … Individually arrayed constructs, up to ~150 Kb in length  Pooled libraries such as sgRNA, promoter or MoClo assemblies …
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Plant Program
… With collaborative user projects, the JGI’s Plant Program delves into the … to current problems facing humanity. A major focus are biofuel feedstock species and plant-microbe interactions, … a plant based bioeconomy where plants are a major source of chemical production and contribute to a healthier planet …
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DAP-seq Drives Robust Mapping of Gene Regulation
… Multi-species assays yield an unprecedented view of plant evolution and adaptation.    Understanding how … is like deciphering the complex wiring behind a city’s power grid. Just as the flow of electricity controls when … adaptation. “You learn a lot more than you would from each one individually,” Baumgart added. “By combining these data, …
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JGI Launches Latest Strategic Plan
… For the Joint Genome Institute, the end of 2018 was marked by a celebration of contributing over one “petabase” – a quadrillion nucleotide bases of DNA …
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Ray Turner Completes Last Tour of Lab Duty at JGI
… For the last 15 years, Ray Turner has been one constant for the Joint Genome Institute. On July 1, … as a typical monthly JGI All-Hands Meeting, after a couple of perfunctory items, the agenda went off the rails – … as a rehired retiree, he added, his offer for a carpool ride to Berkeley from the Peninsula is still good. “I …
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Panel Discussion: Launching & Sustaining Startups in Synthetic Biology
… Biology Who’s Invited? All Berkeley Lab Employees and Affiliates. When: August 29th, 3:00 pm – 5:30 pm 3:00 pm – 4:15 … pm – 5:30 pm: Hosted Hoppy Hour @ Calicraft Brewing, Walnut Creek Where:  Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek Featuring a casual, candid, C-level panel discussion with …
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Extracting the Secrets of Secondary Metabolites
… survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … Combining CRAGE with CRISPR provides researchers with a powerful addition to their toolkit to study gene function. … hit the scene in 2019. Now, that power is poised to grow exponentially by combining it with CRISPR.  By employing CRAGE, …
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Pinning Down a Piece of Photosynthesis
… By studying the structure and function of a cyanobacterial protein, researchers have new insights … is difficult. Proteins are tiny, invisible to even the most powerful light microscope, and fickle, often hiding their … Communications takes on the challenge of understanding one of these proteins — and its role in photosynthesis — in …
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Dealing with Drought: Uncovering Sorghum’s Secrets
… Over 40 percent of the cereal crop’s genes respond to drought stress. The … For the study, the team grew two sorghum varieties: one that tolerates better pre-flowering drought stress and a … the leaves. Each week the team would set up a makeshift lab powered by a generator at the KARE field site and then …
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Defining a Pan-Genome for Antarctic Archaea
… Analysis of haloarchaeal metagenomes broadens understanding of … light on the global biogeography in the haloarchaeal gene pool, a team led by University of New South Wales … Halorubrum lacusprofundi from Deep Lake and Rauer 1 Lake, one of the lakes in the nearby Rauer Islands. Additionally, …
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An Earth Month Look at Sustainability Efforts at the JGI
… Sustainable Berkeley Lab maintains a  calendar of Earth Month events throughout April. This year, a new group at the Lab, the Sustainable Garden Club, hosted a DIY … rather than under desk trash bins . These encourage everyone to sort all waste into compost, recycling and trash. …
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Doubling Down on Known Protein Families
… online Oct. 11, 2023 in  Nature highlights the vast array of functional diversity of microbes through a novel approach … in as-yet unveiled microbes. Harnessing the collective power of more than 26,000 microbiome datasets, all … sequences evaded classification. Researchers also tried to hone in on the function of the genes via 3D modeling, and …
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