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Mapping the Earth’s Hidden Fungal Kingdom
… sequenced, roughly half of all genes have completely unknown functions — like a vast library of books written in a … one of the world's most comprehensive collections of fungal genomes. A sweeping analysis published in Nature Reviews … snapshots into dynamic stories of evolutionary innovation. Building a Future-Ready Foundation This massive collection …
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Open Frameworks Training the Next Generation of Scientists
… program for higher education that develops skills in fungal biology and genomics.  Myco-Ed :  The Mycological Curriculum … (JGI), a DOE Office of Science User Facility, and the DOE Systems Biology Knowledgebase (KBase). The JGI and KBase are … genomics. Fungi can be better understood through reference genomes, but unfortunately there are not many available to …
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Workforce Development & Education Outreach
… JGI’s role in enabling complex biological and environmental systems research.  …
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User Programs
… projects that call for expansive sequencing, synthetic biology, and metabolomics capabilities Investigators who … by Letters of Intent. Proposals may include synthetic biology, sequencing, and metabolomics. Proposals may include synthetic biology, transcriptomics, DAP-seq, and metabolomics. …
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Examples: Successful LOIs & Submissions
… terpenoid-mediated plant environment interactions to enable advanced bioenergy crops …
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Strategic Integration of Multiple Bioinformatics Resources for System Level Analysis of Biological Networks
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… Meta-omics datasets show that CRISPR-Cas systems determine mutualism or parasitism between some … are abundant and yet exceptionally small, with mini genomes to match. As a result, they cannot process all of … coexist is key for understanding their impact on wider ecosystems, but these symbiotic interactions are difficult …
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A Model System for Perennial Grasses
… Panicum hallii genomes offer insights to drought tolerance. The Science … hallii (Hall’s panicgrass), by generating two complete genomes from varieties that diverged over a million years … Science Program , JGI sequenced and assembled near-complete genomes of P. hallii var. hallii (99.2% complete) and P. …
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Trent Northen
… founded what is now the JGI Metabolomics Program to provide advanced metabolomic methods available to JGI users.  Dr. … Northen’s research is focused on using metabolomics to link genomes with environments to understand how webs of microbes … mass spectrometry approaches and model laboratory ecosystems (EcoFABs). …
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2024 Progress Report
… The Integrative Genomics Building (IGB) seen above is home to the DOE Joint Genome Institute (JGI). Researchers from the DOE Systems Biology Knowledgebase (KBase), the National … of Energy Office of Science user facility, we provide advanced genomic capabilities, large-scale data, and …
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The first 10 years of the international coordination network for standards in systems and synthetic biology (COMBINE)
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Advances and challenges in understanding evolution through genome comparison: meeting report of the European Molecular Biology Organization (EMBO) lecture course “Evolutionary and Comparative Genomics”
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