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… snippets of microbial genomes directly from environmental sequence data, by piecing each genome together from large mixtures of genomic sequences. A complementary approach to this is single cell … are first separated, and their genomes then amplified and sequenced individually, offering scientists the opportunity …

… practices, development of standards and processes for data quality and sharing, and data workflows and management best …

… why she works on this alga, how researchers managed to sequence its genome, and what it has to teach us about other …

… genomes. She and her colleagues have generated a high-quality, phenotyped mutant library in Chlamy, as the alga is … Research (BER) to harness the combined expertise and resources of two of the national user facilities stewarded … can combine EMSL’s unique imaging, omics and computational resources with JGI’s cutting-edge genomics, DNA synthesis …

Cas9 needs guide RNA to lead it to the correct sequence to snip — but not all guides are effective. To … approach: CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, … , the scientists thus set out to identify which sgRNA sequences were reliable. In an elegant, quantitative screen, …

… in Wang’s group on developing an algorithm for RNA-Seq assembly. RNA-Seq is a technique for profiling the small … users to simultaneously run several programs for RNA-Seq assembly to determine which is best for the task at hand. …