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Streamlining Regulon Identification in Bacteria
… technology could speed up associating transcription factors with their target genes. The Science Regulons are a … the third is determining the 5’-ends by 5’-end sequencing, from which those promoter sequences recognized by a given … experimentally verified in S. coelicolor . With results from the research, RIViT-seq data have increased the …
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DOE JGI Interns Share Their Summer Experiences
This summer, the DOE JGI hosted 10 interns who came from a wide range of backgrounds. Many of them spent the … genomic data at a computer; a few had the opportunity to spend time out in the field, work at the lab bench, and also do …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… scientists are now getting more complete genomic results from single cells. The Science Studying the  genomes of … the earth, but most species do not grow easily in the lab. To access the genomes of uncultured  microbes , scientists … sequencing. Shotgun metagenomic sequencing takes much less time than its single-cell counterpart. In this approach, DNA …
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A One-Stop Shop for Analyzing Algal Genomes
The PhycoCosm data portal allows anyone to freely investigate the genes of more than 100 algae. The … and what they do. Summary The name PhycoCosm stems from the Greek phykos , meaning seaweed. Seaweeds are algae, … data are available, a user can also analyze gene expression from published experiments; study DNA methylation, which …
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Celebrating a Decade of Science through the JGI-UC Merced Genomics Internship Program
What started with 2 interns in the summer of 2014 has grown to a total of 75 with the inclusion of the 2023 cohort. Each … our largest and most successful one. It’s proven to be a really good model for us that we try and continually … all the work that went into this program was the feedback from the graduate student interns; “it changed what I want …
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Genome sequence of the mud-dwelling archaeon Methanoplanus limicola type strain (DSM 2279T), reclassification of Methanoplanus petrolearius as Methanolacinia petrolearia and emended descriptions of the genera Methanoplanus and Methanolacinia
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JGI Accepts 17 Proposals for Community Science Program
Monitoring Inter-Organism Interactions Within Ecosystems Latest … (Berkeley Lab). They were selected through peer review from 41 full proposals out of 50 letters of intent … in the Antarctic Peninsula. Additionally, the proposal from Viola Krukenberg at Montana State University …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… in improving and applying a method that allows researchers to quickly modify diverse bacterial genomes. In 2019, the … relatives with the BGCs, JGI scientists could relieve BGCs from their former genetic repression, enabling scientists to … doubling the amount of DNA that can be inserted at a time. In a  project detailed in  ACS Synthetic Biology , …
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Frederik Schulz
Dr. Schulz employs multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to find novel functions that may impact microbiome structure … University of Vienna (Austria) … Krinos et al. 2024. Time-series metagenomics reveals changing protistan ecology …
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Genome evolution in the allotetraploid frog Xenopus laevis
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The Genome of the Western Clawed Frog Xenopus tropicalis
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Ancient Algae Reveal Secrets of Plant Evolution
… the genes of land plants’ closest algal relative,  Zygnematophyceae , scientists have enhanced our understanding of how early plants transitioned from water to land. Key gene groups involved in stress … complex structures and adapt to changing environments — ultimately allowing them to adapt to life on land. Learning …
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