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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria

… that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and his team … an important addition to the synthetic biologist’s toolkit: a technique for c hassis (or strain)-independent r ecombinase- a …

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Approved Proposals

… below to view a downloadable pdf of accepted proposals from previous fiscal years for our Community Science Program (CSP) as well as the Facilities Integrating Collaborations for User Science (FICUS) program. …

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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways

… This is where the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … PI on this project. “I view the program as an excellent platform to build collaborative research initiatives.” Yasuo … developed thousands of DNA constructs encoding a molecular tool to repress targeted genes in the organism. The team …

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A Novel Freshwater to Marine Evolutionary Transition Revealed within Methylophilaceae Bacteria from the Arctic Ocean

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Assembly of Robust Bacterial Microcompartment Shells Using Building Blocks from an Organelle of Unknown Function

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Sediment microbial communities in Great Boiling Spring are controlled by temperature and distinct from water communities

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Lessons from Two Design–Build–Test–Learn Cycles of Dodecanol Production in Escherichia coli Aided by Machine Learning

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Phototrophic Co-cultures From Extreme Environments: Community Structure and Potential Value for Fundamental and Applied Research

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Critical biogeochemical functions in the subsurface are associated with bacteria from new phyla and little studied lineages