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… gives an overview of the JGI's Genomes OnLine Database and why curated metadata matters. …
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Since joining the DOE Joint Genome Institute in 2016, Dr. Otani has been studying secondary metabolism in … is particularly interested in understanding how, when and why microbes decide to produce which metabolites. … BS, … in bacterial RiPP biosyntheses. J Ind Microbiol Biotechnol. 2023 Feb 17;50(1):kuad005. Otani H, Udwary DW, Mouncey NJ. …
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… snippets of microbial genomes directly from environmental sequence data, by piecing each genome together from large mixtures of genomic sequences. A complementary approach to this is single cell … User Facility, is supported under Contract No. DE-AC02-05CH11231. This work was supported in part by a Natural …
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… to the global research community. Published January 17, 2025 in Science Advances , researchers at the U.S. … genomic biodiversity. Using publicly available genome sequence data generated over the past three decades, their … group. “Turns out that despite all the genomes we've sequenced, we've only scratched the surface.” The study, …
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Cas9 needs guide RNA to lead it to the correct sequence to snip — but not all guides are effective. To … approach: CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, but these …
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