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Busting the Unbreakable Lignin
… New evidence shows anaerobic fungi can degrade the hardiest of plant components   The Science There are three main … anaerobic fungi (Neocallimastix californiae) on sorghum, switchgrass and poplar, then monitored changes to the … JGI data portals and pipelines helped identify potential genes responsible for lignin deconstruction. (The JGI also …
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2022 Progress Report
… Pictured is a timelapse of the Integrative Genomics Building … Area are also co-located in the IGB. Vision The vision of the U.S. Department of Energy (DOE) Joint Genome …
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Cultivating Symbiotic Antarctic Microbes
… cultures reveal they are symbionts and not free-living organisms. The Science Researchers employed multiple … The Impact The Antarctic lakes are a “treasure trove” of unknown microbes that play critical roles in … was discovered with proteomic analyses. The species harbors genes encoding SPEARE proteins—which contain  s erine  p …
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Eelgrass Proves to Be Much Younger Than We Thought
… less than previously believed.  The Science Eelgrass, one of the most abundant plants in the ocean, originated in Japan before spreading around … to providing a more detailed timeline of eelgrass’s evolution, the study also shows the younger meadows in the … Sequencing Program (CSP 502951, 2016, Population and evolutionary genomics of host–microbiome interactions in …
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Help from Citrus’ Bitter, Hardier Cousin
… The chromosome-scale genome sequence of trifoliate orange yields clues to disease-resistance that … orange. Otherwise known as  Poncirus trifoliata , it’s an evolutionary cousin of the  Citrus genus, which gives us … Journal.  this study included the discovery of candidate genes that confer resistance to citrus greening disease. …
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Bioenergy sorghum stem density increases threefold following internode elongation due to continued accumulation of lignified cell walls and complex regulation of genes involved in cell wall biosynthesis
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Advances and challenges in understanding evolution through genome comparison: meeting report of the European Molecular Biology Organization (EMBO) lecture course “Evolutionary and Comparative Genomics”
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Interdisciplinary delegation from the University of Duisburg-Essen explores collaborative opportunities with Lawrence Berkeley National Laboratory
… A two-day kick-off meeting held at Lawrence Berkeley National Laboratory (Berkeley … also intensively discussed. The Berkeley Synchrotron Infrared Structural Biology (BSISB) Program for the … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … contains about 6% of the human genome . They discovered genes linked to conditions such as cardiovascular disease, … with the HudsonAlpha Institute for Biotechnology.   Publications Grimwood, J., Gordon, L., Olsen, A. et al. The …
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Len Pennacchio
… In 2003, Dr. Pennacchio joined the DOE Joint Genome Institute and has focused on applying state-of-the-art molecular methods to address wide-ranging … of Genetics at Stanford University where he uncovered the genetic cause of a rare form of human epilepsy and …
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Mining Metagenomes for Cas Proteins
… Institute.  The Science Researchers report the discovery of miniature Clustered Regularly Interspaced Short … (that is, repair gene mutations, and either delete or add genes in a precise fashion) has applications across many … range of applications for CRISPR-Cas systems. It also underscores the untapped potential waiting to be unearthed in …
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Novel heavy metal resistance gene clusters are present in the genome of Cupriavidus neocaledonicus STM 6070, a new species of Mimosa pudica microsymbiont isolated from heavy-metal-rich mining site soil
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