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… virus-host dynamics, computation helps fill in what cultivation can’t. The Science At first, viruses are merely … Office of Science, Biological and Environmental Research, Early Career Research Program awarded under UC-DOE Prime …

… and billions of years ago. DAN UDWARY: Like, really early on. [LAUGHING] JACKIE WINTER: Way back in time. ALISON …

… and quality of finished product depend on genome. Selected genomes will be improved based on feasibility and scientific … Single Particle Sort Draft quality assembly of amplified genomes from sorted cell(s)/particle(s), many unordered … Single Particle Sort Draft quality assembly of amplified genomes from sorted viral particles, unordered contigs …

… sort of foundational starting point. And they would work linearly through all of the possibilities until they reached … in quite unusual ways sometimes. And some of the really early work – it took a long time for .. I mean, structural … technology from UCSD, which is doing pattern recognition in comparing spectras to one another. And community-based …

… 2014), unearthing hundreds of thousands of new viral genomes and their predicted hosts (Nature 2016, Science … 2018, Molecular Cell 2019) and massive reconstruction of genomes from uncultivated microbes (Nature 2019). Other … the quality and completeness of metagenome-assembled viral genomes. Nature Biotechnol . 39(5):578-585. Nayfach S, et …

… Those remain challenges.   DAN: Sure. I know it’s early on, but you do have a project with the JGI. It’s doing …   DAN: Got it.    NANCY: And this is really to complete the genomes, and I’m really thankful for this. It sort of goes … do Illumina sequencing and we can get – thousands of fungal genomes are floating out there – some are private – that, …

… for you, we sequenced thousands for you or thousands metagenomes. And I think also the quality that we provide. So for fungal and for a lot of our eukaryotic genomes, all our eukaryotic genomes. Fungal plant, algal … the annual CSP call. That call is supposed to come out in early next year. Same for the FICUS, we’re working with EMSL …