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Dr. Yasuo Yoshikuni has been head of the DNA Synthesis Science Program since 2015. The mission … engineering, and biosystems design for DOE-mission-relevant discovery and applications. This program has supported over … … DNA Synthesis Science Program … Education … Selected Publications … Awards and Honors …

… metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more nuanced … to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of gene … area in the DNA, to determine which targets might benefit from an intermediate level of expression. Similar to the …

Genomics call is to enable users to perform state-of-the-art functional genomics research and to help them … synthesis and ‘omics capabilities to enhance understanding of gene and genome function, particularly those not readily … and analysis will be paid for by the Department of Energy’s funding of the JGI. There is no cost to the user …

… the JGI has pioneered, including single-cell genomics and metagenomics. The GEBA initiative has also utilized a very … seen with reference isolates. “For secondary metabolite discovery in particular, this is a cautionary tale on their … resource, but also yielding and supporting many high-impact publications ,” emphasized Markus Göker, who managed the …

… into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for bioenergy, … automations for DNA design, assembly and analysis Overview of synthesis products The JGI DNA Synthesis platform enables users to validate hypotheses generated from mining genomic data by designing and assembling …

… ice in the Arctic has decreased by more than 30% in terms of quantity and thickness. Replacing older, thicker ice with … and climate resilience of algae — for potential use as biomass or in biomass conversion to biofuel. Summary Water … Sciences and Engineering Research Council of Canada (NSERC) Discovery program grants to C.L. Support from the Canada …

… synthesis, and metabolomics at the JGI for projects of relevance to Department of Energy (DOE)  Mission Areas . … aims to advance genome science-based scientific research from a broad range of disciplines. Three calls fall under … more customized analysis, the JGI also participates in publication of results. See more details on our Review …

Celebrating 25 years of genomics research 2022 marked the JGI’s 25th anniversary. We revisited a number of notable achievements that showcase our collaborations and … the JGI’s 25th anniversary, the JGI mural references dozens of iconic JGI contributions to advancing the frontiers of …

… landscape of vertebrate genomes, which led to the discovery of thousands of genetic switches implicated in … Computational Biology , Nucleic Acids Research . Over 80 publications in peer-reviewed journals including Nature, … LA, Tringe SG, Visel A , Woyke T, Wang Z, Rubin EM (2011). Metagenomic discovery of biomass-degrading genes and genomes …

Tracking evolution of symbiotic lifestyles across multiple fungal lineages. The … change. For example, the number of plant cell wall-degrading enzymes such as ligninases and cellulases were … to white rot fungi. Additionally, some of the saprotrophic genes found in the mycorrhizal species, such as nutrient …