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Molecular Mechanisms Driving Switch Behavior in Xylem Cell Differentiation
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What Happens Underground Influences Global Nutrient Cycles
… for User Science (FICUS) program, two Department of Energy (DOE) Office of Science national user … Molecular Sciences Laboratory (EMSL) and the  DOE Joint Genome Institute (JGI)—have selected 11 proposals for … rainforests, which play a key role in the global carbon cycle. Tfaily’s team is specifically interested in …
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Who We Are
…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national … at Lawrence Berkeley National Laboratory. The JGI consists of 225 researchers and support staff in the Integrative … The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a high-throughput AI-centric …
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JGI@25: A Single Cell, Myriad Microbial Discoveries
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … quantities of DNA derived from individual environmental cells. The proof of principle study built off earlier … year, the JGI team reported the first closed and finished genome derived from an uncultured bacterial single cell – a …
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Plant Program
… to current problems facing humanity. A major focus are biofuel feedstock species and plant-microbe interactions, … a plant based bioeconomy where plants are a major source of chemical production and contribute to a healthier planet … improve the accuracy of functional predictions and speed up genome analysis. Additionally, the Plant Program is …
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Multicellular magnetotactic bacteria are genetically heterogeneous consortia with metabolically differentiated cells
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DOE Metrics
… (Trillions) Operating Hours Goal  Actual Total*   Actual % of Goal   Goal (hours)**   Actual Total   Actual % Goal   FY … developments for improving microbial, metagenomic, or plant genome assemblies. [Download PDF] Q2 – Report on progress … the interpretation of microbial, metagenomic, or plant genomes. [Download PDF] End-of-year Goal – Develop one new …
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Extensive epigenetic reprogramming during the life cycle of Marchantia polymorpha
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Len Pennacchio
… In 2003, Dr. Pennacchio joined the DOE Joint Genome Institute and has focused on applying state-of-the-art molecular methods to address wide-ranging questions existing in biology. He holds joint … Len Pennacchio is the JGI's Deputy of Genomic Technologies. oClick to learn more about the …
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Complete Genome of Oil-Rich Alga Reveals Ideal Platform for Bioengineering
… Streamlined genome with precise gene targeting transforms oil-producing …   The Science Scientists have fully decoded the genome of an oil-producing green alga, and demonstrated precise … in the genome in the November 2025 issue of The Plant Cell. Auxenochlorella is an allodiploid hybrid of two …
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Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… di-GMP (Guanine Monophosphate) is found in nearly all types of bacteria and interacts with cell signaling networks that … illumination to produce a signal, making them useful in a wider range of environments. This new technology enables … at the University of California, Berkeley and the Joint Genome Institute, a DOE Office of Science User Facility, …
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You Can Move, But You Can’t Hide
… to replicate themselves and spread from cell to cell. Two of the most common forms of MGEs are viruses and plasmids. … Lead Nikos Kyrpides at the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility at … cellular level, scientists can better understand ecosystem-wide processes. Summary geNomad is an annotation and …
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