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Natural Prodcast Episode 19: Bill Fenical
… to talk to one of the real legends of natural products, Professor Bill Fenical from Scripps Institution of Oceanography … products, getting into the ocean and looking for molecules from the very beginning of the field. I learned a lot so … for culturing, and then of course using modern phylogenetic tools measuring genes, the 16S gene, and comparing it with …
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Natural Prodcast Episode 18: A CSP Primer
Natural Prodcast is back again for another round of episodes. If you stick around for the next few months, you’re … on from JGI to do real journalism, and we wish her all the best. Later on, I’ll introduce my new co-host, who I’m really … did those sequences go? Like, what are the other scientific tools we offer people? TANJA WOYKE: Yeah. Also a really good …
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How Maize Makes An Antibiotic Cocktail
Maize produces a family of compounds that protects it against infections — using surprisingly few enzymes. The Science Maize ( Zea mays ) produces a plethora of antibiotics called zealexins. Even though …
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JGI Portals
Our data platforms are a key resource for the broader scientific community and require … users. … Download plant, algal, fungal and microbial genomes and metagenomes — top-quality genomic data, open to all … unified access to all JGI genomic databases and analytical tools for all JGI sequencing projects. In 2021, the JGI …
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Natural Prodcast Episode 5: Brad Moore
UC San Diego and Scripps Institution of Oceanography. (Courtesy of B. Moore) DAN: This is the second of our … a great chat with him.  I kind of lost count of how many times Brad used the words “fun” and “magical” when describing … us is connecting genes to chemistry to really expand the toolbox of biocatalysts that we work with. Seemed like …
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Natural Prodcast Episode 6: Marc Chevrette
… quality isn’t as good as what you’ll hear in other episodes, but it’s not terrible. I was able to clean it up quite a bit, and the conversation was so interesting that I wanted to include it. This is a conversation … and I’m really excited about it. Because now we have the tools through genomics, and metabolomics, to ask these …
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Learning to Look
… significantly expands inovirus diversity. To answer the question, “Where’s Waldo?” readers need to look for a number of distinguishing features. Several characters may be spotted with a striped scarf, … in the  Environmental Genomics group . Training the Search Tool Inoviruses are stealth agents that can enter and exit …
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Accelerating Metagenomics Discoveries with Deep Learning
Lab) and other institutions shared their works-in-progress with 86 participants in an online workshop to harness … said Sevim.  While there are alignment-free methods for nucleotide searches, such as  Mash and  BBsketch , whose … is JGI software developer Brian Bushnell, no alignment-free tool exists for proteins. (And while Mash and BBsketch can …
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A Complex Confection Decoded: Sugarcane Reference Genome
… major crop without a reference quality genome and now crop researchers can work toward advancing sugarcane … biotechnology. The Science Considered the world’s most harvested crop by tonnage, sugarcane accounts for 80% of global … Botany (IEB) was supported by the ERDF project “Plants as a Tool for Sustainable Global Development” No. …
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You Can Move, But You Can’t Hide
Researchers at the JGI develop a tool to quickly and accurately identify mobile genetic elements like plasmids and viruses. The Science Mobile genetic elements (MGEs) are genetic … be found in virtually all of Earth’s ecosystems. A software tool  recently described in  Nature Biotechnology  called …
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Marine Microbe Contains Multitudes
… dive into microbial genomics reveals one bacterial species is made of four ecologically distinct groups with different lifestyles. The Science The bacterium SAR324 is unusually … also processed using the JGI-developed software suite, BBTools , and relying on the JGI Integrated Microbial Genomes …
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Better Genome Editing for Bioenergy
CRISPR-Cas9 is a powerful, high-throughput gene-editing tool that can help scientists engineer organisms for … lead it to the correct sequence to snip — but not all guides are effective. To ensure the gene editing tool will make the right cut, researchers created a set of guide RNAs that were effective …
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