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Genome sequence of the moderately thermophilic, amino-acid-degrading and sulfur-reducing bacterium Thermovirga lienii type strain (Cas60314T)
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Genome-wide functional screens enable the prediction of high activity CRISPR-Cas9 and -Cas12a guides in Yarrowia lipolytica
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Green Algae Reveal One mRNA Encodes Many Proteins
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… A final recent advance in CRAGE is the addition of CRISPR enzyme Cas9. Originally, CRAGE was only used to  insert genes of interest. But now, with Cas9, CRAGE can be used for precise genome editing. This …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… Meta-omics datasets show that CRISPR-Cas systems determine mutualism or parasitism between some … the microorganisms had a close relationship. Then, using metagenomes and metatranscriptomes generated by the U.S. …
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Natural Prodcast Episode 15: Katherine Duncan
… the last couple of conversations that we’ve had on this podcast, the idea of taking all the different natural products … with genomics and the kind of things that I do with genome mining. And figuring out how to put that together, I think, … a good parallel there with what we talked about with genome mining, Alison, where once you have a few of the pieces in a …
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Thermoacidophilic proteins for biofuel production
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The obligate alkalophilic soda‐lake fungus Sodiomyces alkalinus has shifted to a protein diet
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Comparative analysis of carboxysome shell proteins
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Extreme-Scale Many-against-Many Protein Similarity Search
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Extracting the Secrets of Secondary Metabolites
… CRAGE-CRISPR combo helps further demystify biosynthetic gene … a proof-of-concept study in which researchers paired CRISPR and CRAGE technologies. While CRISPR (Clustered Regularly Interspaced Short Palindromic …
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LmbE proteins from Bacillus cereus are de‐N‐acetylases with broad substrate specificity and are highly similar to proteins in Bacillus anthracis
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