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Natural Prodcast Episode 2: The Primer, Part 2
… is a bacterial sacred metabolite, and ergot alkaloids come from fungi, and Taxol from plants. Plants, fungi, bacteria, … were a really common source for people to try to find new medicines for a long time. But we know now that most of … It’s an evolution of primary metabolism. So a lot of the genes and the DNA that’s used for secondary metabolism, they …
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Sequencing Submission Requirements for DNA Synthesis
… add the characters “.gb” (no quotes, just .gb) to the end of your file name. …
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Natural Prodcast Episode 3: The Primer, Part 3
… by what’s called “find and grind”. So you would find some new source that you hadn’t explored before. Like, you know, … maybe it’s a new culture of a new bacteria that you pulled from the soil, maybe it’s, you know, we talked about … and actually get to the DNA sequence – sequences for the genes that code for the proteins that produce secondary …
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Ancient Algae Reveal Secrets of Plant Evolution
… over 600 million years ago. The Science By studying the genes of land plants’ closest algal relative,  … enhanced our understanding of how early plants transitioned from water to land. Key gene groups involved in stress … scientists sequenced the genomes of four  Zygnematophyceae algae, which were isolated from diverse freshwater …
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Publication Policy
… The purpose of this policy is to establish communication norms around JGI contributions, ensure that all contributors to a research project are appropriately recognized and credited … is done in a timely fashion. The publications resulting from such efforts should specify the collaborative nature of …
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Data Policy
… Data produced and released by the US Department of Energy (DOE) Joint Genome Institute (JGI) are subject to … the need to have a limited and time-sensitive protection of certain types of data to support their use by those generating data. The JGI Data Policy applies to research data and analysis products (referred to as “data” …
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2021 JGI Proposal Call Brings New Investigators into Community Science Program
… Accepted proposals emphasize JGI interests in algae and secondary metabolites. A total of 27 proposals … Laboratory (Berkeley Lab). The accepted proposals come from 80 full proposals, resulting from 95 letters of intent. … metabolite-producing environmental bacteria from the Tiny Earth collection. The work builds upon a pilot project …
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Events
… New Lineages of Life (NeLLi) Symposium … represented at conferences year round; find out where our researchers will be presenting next. Go here to learn about …
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Making a Lichen Together
… autonomy; they can be isolated and grown separately from each other. A possible explanation, according to the … clonally. Yet its genome revealed that the alga has all the genes needed for meiosis, and thus can rapidly create … One of their abilities that’s  now getting more scrutiny is how lichen is able to survive drying out to a …
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Gene Expression: From On-Off Switch to Dial
… metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more nuanced … approach to fine-tune gene expression. They tested this new methodology in yeast ( Saccharomyces cerevisiae) to … area in the DNA, to determine which targets might benefit from an intermediate level of expression. Similar to the …
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Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet
… huge amount of natural diversity and say, ‘Yeah, there are genes out there that affect this phenotype.’”  Results from A “Massive Amount” of Sequencing  Seed dispersal is … it was involved in shattering by turning it off. “It’s a new shattering gene variant identified in a natural …
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A Cost-Efficient Way to Convert Yeast into a Cell Factory for Hydroxyapatite
… Innovative technology from this biomanufacturing collaboration is available for … hydroxyapatite, a high-value biomaterial with a wide range of industrial applications. The team was led by researchers … $1.4 million annually.  The team is working on developing new microbial strains that can synthesize other bio-based …
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