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gRNA-SeqRET: a universal tool for targeted and genome-scale gRNA design and sequence extraction for prokaryotes and eukaryotes
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Uncovering Sequence and Structural Characteristics of Fungal Expansin‐Related Proteins With Potential to Drive Substrate Targeting
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Len Pennacchio
… NIH 2019   Lawrence Berkeley Laboratory Director’s Award for Exceptional Scientific Achievement 2017-  Adjunct … Program Defining the vast landscape of gene regulatory sequences in the human genome. Understanding how variation in regulatory sequences influences human disease/biology. Assessing and …
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Promoting the Power of Viral Metagenomics
… hydrothermal vents – and computationally identifying which sequences represent viruses that were present in the sample. …
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Large Direct Repeats Flank Genomic Rearrangements between a New Clinical Isolate of Francisella tularensis subsp. tularensis A1 and Schu S4
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Crystal structure of the FRP and identification of the active site for modulation of OCP-mediated photoprotection in cyanobacteria
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A hemoprotein with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
… Center, JGI staff worked around the clock to generate the sequences of these three chromosomes. In 2004, they published the sequences of these three chromosomes. These sequences account for approximately 12% of the total human …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… to the way many organisms function, they have a sense of why nitrogen metabolisms can be so varied.  As evolution has … different Swiss Army knives — explaining a bit more about why and how nitrogen metabolism is so robust and varied.  …
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JGI Early Career Researchers Featured in mSystems Special Issue
… recent Nature Communications paper, uncovering giant virus sequences in soil for the first time. A second approach … genomes directly from the environment and focuses on sequence reads to link mobile elements such as plasmids to … genome assembly from metagenomes. This is a critical step toward better understanding the impact of viruses upon …
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Microbial Genomics & Metagenomics (MGM) Workshop
… workflows for computational analysis and interpretation of sequence data. IMG/M is a web-based platform that provides access to the wealth of public microbiome sequence data and enables the user to analyze these data … with existing bioinformatic methods to bridge the gap from sequence to biology. …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… National Laboratory, used single-cell sequencing to sequence both a cell’s genome and detect accompanying viral sequences, which would suggest the virus had been infecting … abundance of a virus relative to its host (inferred through sequence data) can suggest different predatory behaviors. A …
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