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In honor of the JGI's 25th anniversary in 2022, we have revisited a … technology described by the Nobel Foundation as having “a revolutionary impact on the life sciences.” Building upon … refine and improve the process of finding novel Cas genes and CRISPR systems. The collaboration has resulted in …

… still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have … (BDO). To do so, the yeasts received fine-tuning of gene expression through genetic rewiring with CRISPR-Cas9 that …

… well ] The Science The recipe for growing algae as a source of sustainable biofuels seems fairly simple: place these … stresses, and its transcriptome to learn more about which genes expression patterns. The analysis led to the identification …

Meta-omics datasets show that CRISPR-Cas systems determine … The Science Within the archaeal domain, there is a group of tiny hitchhikers. These organisms are abundant and yet … Then, using metagenomes and metatranscriptomes generated by the U.S. Department of Energy (DOE) Joint …

Marcel is in charge of several production pipelines (gene calling, functional …

… archaea are estimated to produce 500 million tons of methane a year, which is over half the total global … methanogenic archaea use one of three pathways for methanogenesis: hydrogen-dependent and CO2-reducing, or … collected. The team noticed some of the genomes diverged evolutionarily from other previously discovered genomes. …

The Joint Genome Institute's DNA Synthesis Platform capabilities … into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for bioenergy, … automations for DNA design, assembly and analysis Overview of synthesis products The JGI DNA Synthesis platform enables …

New evidence shows anaerobic fungi can degrade the hardiest of plant components   The Science There are three main … JGI data portals and pipelines helped identify potential genes responsible for lignin deconstruction. (The JGI also … conducted RNA sequencing and alignment to the reference fungal  genome . The study’s pivotal NMR (nuclear magnetic …