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JGIota: Looking Back at Methane-Making Microbes
Learn more
2024 Progress Report
… for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide … processed 13,700 metabolomics samples With our users, 247 publications were published   … Our primary objective is to … spatial transcriptomics, and cell- and cell-free expression platforms.  … We closed our 2018 Strategic Plan at …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … with the HudsonAlpha Institute for Biotechnology. Publications Grimwood, J., Gordon, L., Olsen, A. et al. The …
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Engagement Webinar: How to Successfully Apply for a CSP Proposal
… and relevance to the DOE’s mission.  Have someone proofread your proposal to make sure the goals, experimental … include a reference or citation in a proposal? A: If you’re presenting preliminary data that’s been published, or if you want to …
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JGI@25: Studying Sorghum’s Survival Skills
In honor of the JGI's 25th anniversary in 2022, we have revisited a … reference genome for Sorghum bicolor . Since then, 2,993 publications, 107 patent applications, and 53 patents have … genome. Compared to shorter, grain-producing varieties previously sequenced, this line is sweeter, taller, and …
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JGI@25: Expanding Metagenomics to Capture Viral Diversity
In honor of the JGI's 25th anniversary in 2022, we have revisited a … and  this most recent version is six times larger than the previous one . To identify so many genomes, JGI researcher … and metagenomes, called geNomad (watch Antonio Camargo present on IMG/VR v4 at the 2022 VEGA meeting below). …
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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
… to sift and characterize RNA virus sequences.  A zoo once offered a coloring book featuring polar bears in winter … not just crops, animals and humans, but also microbes whose presence or absence can impact the planet’s nutrient cycles. … United States, and is working to address some of the most pressing challenges of our time. For more information, …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
A special issue of Synthetic Biology celebrates research enabled by the JGI … more than 10 papers, including two Nature Plants publications, in five years, have come out of the … in the Synthetic Biology special issue, Modular cell-free expression plasmids to accelerate biological design in cells , …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
The Science Within the archaeal domain, there is a group of tiny hitchhikers. These organisms are abundant and yet … mini genomes to match. As a result, they cannot process all of the chemicals they need to survive. To fill in their nutrient gaps, they must latch onto a larger host — often, a fellow archaeal microbe. Understanding how these …
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How to Target a Microbial Needle within a Community Haystack
A workflow for capturing the genetic make-up of specific uncultivated microbes from complex environmental … complex community and then separating out the sequences representing microbes of interest. When the microbe of … can then be made available to JGI users in order to address pressing energy and environmental scientific challenges. … …
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Applying Viral Genomics Expertise to Understanding the Human Virome
… viruses outnumber the microbes by at least another order of magnitude. For years, scientists at the DOE Joint Genome … into groups that can be compared across studies, (ii) predicting which hosts these viruses are likely to infect, … , an integrated machine learning framework to maximize host prediction for metagenome-derived viruses of archaea and …
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Fields of Breeders’ Dreams: A Team Effort Toward Targeted Crop Improvements
… crop and ornamental seeds sold for the upper Midwest are often very different than those bred for Texas. Identifying … 10 experimental gardens located in eight states spread across 1,100 miles. Switchgrass is a perennial grass … have different levels of performance,” Juenger said. “The novelty here is that we’re trying to actually figure out …
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