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JGI announces 2024 Functional Genomics awardees
…   Each year, the JGI accepts proposals for state-of-the-art functional genomics research from reseachers who … sustainable biomaterials, and developing high-throughput methods to reveal metabolic pathways that could ultimately …
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Enlarging Windows into Understanding Gene Functions
JGI innovates protocol revealing how genetic variations in sequences affect traits. In a text file, the rows of letters A, T, C and G appearing over and over in a … sequencing or DAP-seq. The technology was developed by Ronan O’Malley , who leads the Sequencing Technologies …
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2024 Progress Report
The Integrative Genomics Building (IGB) seen above is home to the DOE … for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide … processed 13,700 metabolomics samples With our users, 247 publications were published   … Our primary objective is to …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
In honor of the JGI's 25th anniversary in 2022, we have revisited a … with the HudsonAlpha Institute for Biotechnology. Publications Grimwood, J., Gordon, L., Olsen, A. et al. The …
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Busting the Unbreakable Lignin
New evidence shows anaerobic fungi can degrade the hardiest of plant components   The Science There are three main … irrefutable evidence that lignin can, in fact, be deconstructed without oxygen. Lead author Tom Lankiewicz …
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JGI@25: Studying Sorghum’s Survival Skills
In honor of the JGI's 25th anniversary in 2022, we have revisited a … reference genome for Sorghum bicolor . Since then, 2,993 publications, 107 patent applications, and 53 patents have …
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JGI@25: Expanding Metagenomics to Capture Viral Diversity
In honor of the JGI's 25th anniversary in 2022, we have revisited a … That study multiplied the number of known viral genes by a factor of 16. The same year, the JGI expanded its …
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Extracting the Secrets of Secondary Metabolites
CRAGE-CRISPR combo helps further demystify biosynthetic gene … survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … in 2019. Now, that power is poised to grow exponentially by combining it with CRISPR.  By employing CRAGE, …
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Computationally Classifying Fungal Lifestyles
Machine learning methods were applied on sequenced fungal … genomes to classify gene families. The Science As a proof of concept, researchers developed an algorithm that … genomes of Dothideomycetes, the largest class of fungi, by lifestyles. The machine “learned” to identify data …
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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
Team develops a computational pipeline to sift and characterize RNA virus sequences.  A zoo once offered a coloring book featuring polar bears in winter … Published online September 28, 2022, in Cell , a team led by researchers at Tel Aviv University in Israel, the …
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Accelerating Metagenomics Discoveries with Deep Learning
On July 6, scientists from Lawrence Berkeley National Laboratory (Berkeley Lab) and … insights from metagenomic data. In deep learning, a branch of machine learning, data is passed through algorithms … layers. The architecture of these algorithms, inspired by communication networks found in nature, allows machines …
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Training the Next Generation of Talent
New Graduate Internship Program Builds Bridges Between DOE JGI, UC Merced Days after presenting the results of his summer research at the U.S. Department of Energy … Distinguished Graduate Internship Program. Conceived by Wang and Visel, the program challenges UC Merced graduate …
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