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… analysis leads to identification of biosynthetic gene clusters for novel secondary metabolites for multiple … of bacteria with diverse metabolic activities. Found in marine and terrestrial environments, actinobacteria play … Group. Many of these bacterial and archaeal genome sequences have been generated using techniques that the JGI …

… Program aims to generate large datasets to explore sequence-function relationships, advancing the discovery of … engineering traditionally utilizes a stepwise approach for strain development, requiring cycles of construct design, … Science Group supports researchers exploring how to convert sequence into functional assessments. The team has a …

… a computational pipeline to sift and characterize RNA virus sequences.  A zoo once offered a coloring book featuring … in various shades of white. To researchers searching for sequences of RNA viruses in large data sets, their work may … to defend against RNA,” Roux noted, “although it’s unclear why this is so rarely detected.” Developing Approaches for …

… Our research focuses on the assembly of metagenomic sequence data into microbial genomes, which is of … Profile HMM search across all IMG metagenomes, capturing sequence diversity for proteins of interest. … better understanding of complex ecosystems within hard to sequence and assemble samples, such as those from soil and …

… I request a culture/slant/DNA of an organism that has been sequenced at the JGI? …

… a method that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and … domesticate some 60 strains, inserting into them a genetic sequence that acts as a “landing pad.” Mouncey adds, “Once … domesticated bacterial strains with novel biosynthetic gene clusters (BGCs). BGCs make diverse molecules of value to …