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Secondary Metabolites Program
… growth, provide critical advantages to the organisms producing them, and are often involved in defense, nutrient … conditions, with only a small portion of the biosynthetic gene clusters (BGCs) being expressed. The program works to … biosynthetic gene clusters (BGCs), advancing pathway analysis, optimization of cell- and cell free-based …
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IMG/M: a data management and analysis system for metagenomes
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Viral Genomics Group
… critical ecosystem functions and affect global nutrient cycling, however they do so under strong constraints exerted by … parameters driving virus:host dynamics in environmental microbial communities. This involves both experimental and … abundant ocean viruses.  Nature . 537:689-93. … Selected Publications … For further information contact the Group …
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Cataloging the Microbes that Manage the Health of River Systems
Database provides details on river microbes in 90% of US continental watersheds. The Science In a recent Nature paper , researchers describe a dataset of microbial genomes sampled from rivers covering 90% of the … resource that provides information at multiple scales from genes to the community level. The Impact Rivers are …
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Natural Prodcast Episode 1: The Primer, Part 1
… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … what we’re calling a Primer. We wanted to try and give a general audience some of the basics of natural products … do this. And also to provide a little more information and context for people who might possibly be interested in …
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The IMG/M data management and analysis system v.7: content updates and new features.
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IMG/M: integrated genome and metagenome comparative data analysis system
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New Lineages of Life Group
… bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, metatranscriptomics, … and biogeochemical cycles. Research Team    … A complete publication list available at Google Scholar. Schulz, C …
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Strain Engineering
The focus of this group, in recent years, has been to bring generalizable … types, in which DNA-based molecules can be chromosomally integrated into a taxonomically diverse suite of microbial …
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IMG/VR v.2.0: an integrated data management and analysis system for cultivated and environmental viral genomes
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Natural Prodcast Episode 21: Elizabeth Parkinson
… right. Welcome back to Natural Prodcast. I did it. I’m keeping to my schedule. This should be coming out on the first … oftentimes will bind to receptors within biosynthetic gene clusters. Specifically, these are Tet repressors that … unknown. And so we've done the sequence similallity network analysis where we look for other receptors with sequence …
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Secondary Metabolites Advisory Committee
… to render advice, guidance, and counsel on the effective management and strategic objectives of the programs. The … relevance and quality. The Committees do not perform management functions nor do they direct the Programs’ management teams on how to operate and manage the particular …
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