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A thermostable Cas9 with increased lifetime in human plasma
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Environmental Genomics Group
… approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … to a better understanding of microbial communities and ecosystem function.  The Environmental Genomics group also …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… Meta-omics datasets show that CRISPR-Cas systems determine mutualism or parasitism between … The Science Within the archaeal domain, there is a group of tiny hitchhikers. These organisms are abundant and yet … how these hosts and hitchhikers coexist is key for understanding their impact on wider ecosystems, but …
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Hiding in Plain Sight: The Globally Distributed Bacterial Candidate Phylum PAUC34f
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Industry Engagement Program
… Facility, the JGI serves more than 2,500 users that predominately come from the public sector: academic and government … joined the JGI in 2017, he brought with him 20 years of industry experience — and an opportunity to expand the … and curated data to support AI applications. In an effort to lead AI-driven genomic innovation to advance …
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Natural Prodcast Episode 4: Nancy Keller
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the science and scientists of … to Natural Prodcast! This is episode 4! From here on out, for a while, we’re going to be presenting some conversations …
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Natural Prodcast Episode 18: A CSP Primer
… It’s been a while, but Natural Prodcast is back again for another round of episodes. If you stick around for the next few months, … do the bioinformatics and to synthesize these results into publication? So there’s this really important because we … Science Program, or CSP. Important Links: The main page for information about CSPs JGI’s Data Release Policy A …
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Special Initiatives & Programs
… Overview The JGI provides sequencing, synthesis, and targeted metabolomics support for DOE-BER funded awards, including awards funded through  … ,  Science Focus Areas  (SFA) opportunities, and the  Office of Science Early Career Research Program .   If … Collection Network (USCCN) to nominate their strains for sequencing, as long as they have a scientific question …
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Pinning Down a Piece of Photosynthesis
… By studying the structure and function of a cyanobacterial protein, researchers have new insights … and cyanobacteria create the air we breathe and the fuel for food webs as they turn carbon dioxide and water into … said.  With this breadth of results, this team has recast a domain of unknown function as Domain Related to Iron, …
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Plant Microbial Interactions Group
… are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental … and associated viruses that all contribute to a dynamic ecosystem. We are interested in how plants self-organize, …
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Bioinformatic analysis of the distribution of inorganic carbon transporters and prospective targets for bioengineering to increase Ci uptake by cyanobacteria
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Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing
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