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… first started out the natural product community was almost 100% bacterial. Only people working in mycotoxins worked … mostly coming out of China and India, very cheap for $100-$200. But you have so many contigs. This is a problem … Basidiomyetes might get to 50. Some of them go to over 100. There. That can be the problem. Whereas the bacteria, …

… ecogenomics. For this role, Dr. Roux can rely on more than 10 years of expertise in the fields of virus ecology and … in a high-altitude watershed soil ecosystem. Microbiome 11, 237 Roux et al., 2023. iPHoP: An integrated machine … in the global microbiome. Nature Communications 12, 3076. Roux et al., 2018. Minimum Information about an …

… a bit embarrassed that we recorded this conversation about 10 months ago. I was pretty green at the time and had some … to my daughters– what did they think would be important in 100 years. Would natural products be important for …

… accurate. And so we told people that if they would curate 1000 entries, that that would earn them authorship of the … the chemical landscape of any sample set. So if you have 100 organisms, and you ferment them under one set of … ROGER:  I’d be surprised if it was still a problem in 10 years. I think that the field – I would say that the …

… vector of choice Glycerol stock of sequence verified clone 102/NA DNA Synthesis Constructs 5-10kb in size Single gene or multiple small genes assembled … change etc) and structural rearrangements, alignment files 114/114 Microbial Transcriptome RNA for expression profiling …

… by the other study co-authors, and reconstructed from these 10 metagenome-assembled genomes (MAGs) representing new … Marker genes for diverse methane metabolisms Of the 10 MAGs reconstructed in the study, five were from … Symposium and for the JGI Annual Meeting closes on March 11, 2019. Novel Yellowstone archaeon belongs to Korarchaeota …

… sequencing, they were able to identify the target genes of 11 sigma factors in Streptomyces coelicolor . The Impact As … and were able to identify the associated target genes in 11 of those. That work published in Nature Communications on … addressed in the study were found to control more than 100 genes, one of which was directly characterized by …

… … Development of cell-free based expression platforms: Only 10-20% of BGCs are expressed under standard laboratory …

… in these gaps of knowledge. In a study published November 11, 2022, in Cell Genomics , the team focused on … combined with nearly 5,000 publicly available ones and 1,100 metagenome-assembled genomes (MAGs) reconstructed from …

Office of Science User Facility (contract no. DE-AC02-05CH11231) with T.J.E. as grantee. J.-C.B. acknowledges the … of Bordeaux Initiative of Excellence (IDEX Bordeaux; (ANR)-10-IDEX-03-02). T.E.M. and R.M. were supported by the …