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… this an awfully long time ago, and she’s been in her new job for a long time now, but I guess you all might not … for culturing, and then of course using modern phylogenetic tools measuring genes, the 16S gene, and comparing it with … We now have cell pellets. And we’re pulling genomic DNA out of those cell pellets. So, we’re about ready to send …

… in how the community itself works together to elicit new metabolite production. And we are also interested in how … local environments, and so they don’t transfer a lot of DNA back and forth, especially across species. And so then … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… have a better understanding of what is what. This is not new. It actually was first proposed by two authors called … I have the feeling that once we have the synthetic biology tools, we finally are in a position to exploit secondary … a look at EvoMining, the non-homology-based genome mining software we mentioned: “ EvoMining reveals the origin and …

… moved there in the early ’60s from Berkeley to work on this new budding field of marine natural products. And was at the … then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … a little bit more difficult. And so getting out clean DNA can also be a challenge there too. So JGI we really have …

… be paid for by the Department of Energy’s funding of the JGI. There is no cost to the user and no granting of funds.   Proposal Call FICUS CSP Large Scale CSP New Investigator CSP Functional Genomics Status CLOSED … capabilities of multiple user facilities Investigators with DOE mission-relevant projects that call for expansive …

The JGI’s Microbial Program focuses on using cutting-edge … resequencing, RNA sequencing and epigenomics. Expansion of sequence space:  The JGI generates reference genomes from … available genomes from three domains of life. It provides tools for analyzing the functional capability of microbial …

… … DAN UDWARY: Hey everyone and welcome back to a new session of Natural Prodcast. I’ve got two things I … which was a very early genome mining company, back when DNA sequencing of natural product pathways was hard and … an undergraduate and not succeeding and still using all the tools from mechanistic enzymology to natural product …

… of their synthases so that we can start to use the DNA sequence to predict or just understand better the … JGI has that really got me into that because we had these new genomes that JGI had sequenced that were of these … restricted niche. And they do need broad host-range genetic tools so it’s more complicated than working with something …

…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national user facility located at Lawrence … researchers and support staff in the Integrative Genomics Building in Berkeley, California.  Our location at the IGB …

… the services of the Arizona Genomics Institute for DNA and RNA extractions to support plant and other efforts. The JGI works closely with DOE computational facilities (e.g., the National Energy … (NMDC)—to provide access to datasets, workflows, and tools to seamlessly expand data functionality. Close …

… empower students through isolation and genome sequencing of new fungal species.  Students collect fungi, sterilize … the Arizona Genomics Institute where high molecular weight DNA is extracted from samples, which is then sent to the JGI … comparative analysis.  MycoCosm provides data and tools via a graphical user interface, ensuring that no …