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DOE Metrics
… (Trillions) Operating Hours Goal  Actual Total*   Actual % of Goal   Goal (hours)**   Actual Total   Actual % Goal   FY … platforms. **Operating Hours target is based on 98% of the total available hours.   FY 2025 DOE Metrics There … (Trillions) Operating Hours Goal  Actual Total*   Actual % of Goal   Goal (hours)**   Actual Total   Actual % Goal   FY …
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Revealing reaction intermediates in one-carbon elongation by thiamine diphosphate/CoA-dependent enzyme family
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Natural Prodcast Episode 17: Cassandra Quave
… Prodcast episode 17. The guest we have this week is Professor Cassandra Quave from Emory University, with joint … very excited today. Usually when we do these interviews, most of the people that I think we’ve talked to so far I … that morning cup of coffee, that is a plant that has a functional activity. It’s a pharmacological agent that acts …
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Strain Engineering
… The focus of this group, in recent years, has been to bring … to no genetic tools enabling heterologous expression and functional exploration.  The developed strains represent an additional phase of user-accessible project types, in which DNA-based …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… With a new methodology, scientists are now getting more complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but most species do not grow easily in the lab. To access the …
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Revealing enzyme functional architecture via high-throughput microfluidic enzyme kinetics
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JGI@25: Mapping Switchgrass Traits with Common Gardens
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … Switchgrass has a large polyploid genome, which means most genes are found as multiple copies across the … has the community of switchgrass researchers grown. After almost two decades of research, switchgrass has become an …
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Offerings & Capabilities
… The central mission of the JGI’s Genomic Technologies department is   ensuring … .  Many users rely on a multifaceted combination of genomic, transcriptomic, proteomic, phenotypic, … is expanding current capabilities in strain engineering and functional assays and supporting new methodologies to …
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Functional diversification within the heme-binding split-barrel family
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Metabolomics
…  Through this identification, metabolomics enables functional genome annotation, improves understanding of the role small molecules play in diverse biological … sheds light on nutrient cycling, and leads to the discovery of new molecules and pathways. The JGI Metabolomics Platform …
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Environmental Genomics Group
… develop computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial lineages, and reconstruct … and viral diversity, leading to a better understanding of microbial communities and ecosystem function.  The … of microbial ecology and metabolism by elucidating the functional potential of hard-to-culture microorganisms. This …
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Biodesign
… support researchers exploring how to convert sequence into functional assessments. This is done by synthesizing genes, … automations for DNA design, assembly and analysis Overview of biodesign products The JGI Biodesign platform enables … and assembling physical DNA constructs that can then be functionally characterized.    We provide custom DNA …
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