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A Functional Mini-Integrase in a Two-Protein Type V-C CRISPR System
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acCRISPR: an activity-correction method for improving the accuracy of CRISPR screens
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Rapid cell-free characterization of multi-subunit CRISPR effectors and transposons
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Protein structure determination using metagenome sequence data
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Exploring microbial functional biodiversity at the protein family level—From metagenomic sequence reads to annotated protein clusters
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Plotting a Model for Virus-Host Warfare Deep Below Ground
Their genomes include short DNA sequences that code for CRISPR systems, which help bacteria resist foreign genetic … biofilm sample collected in 2018. They looked for and found CRISPR spacer sequences in the samples that corresponded to … Huber and Sebastien Ferreira-Cerca, and sequencing of MSI metagenomes within the Census of Deep Life Sequencing call …
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Cas9-Based Metabolic Engineering of Issatchenkia orientalis for Enhanced Utilization of Cellulosic Hydrolysates
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A Natural Mechanism Can Turbocharge Viral Evolution
For a virus with a “head-tail” morphology, this means using proteins on its tail fibers to latch onto a specific target … or DGR. The DGR could mutate the virus’ tail fiber proteins, and thereby allow them to embrace different cells. … sampled all at once from the same environment, called metagenomes. Why? Simon Roux, who led the research team and …
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NMPFamsDB: a database of novel protein families from microbial metagenomes and metatranscriptomes
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Diel rewiring and positive selection of ancient plant proteins enabled evolution of CAM photosynthesis in Agave
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Long-term CRISPR locus dynamics and stable host-virus co-existence in subsurface fractured shales
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CRISPR — a widespread system that provides acquired resistance against phages in bacteria and archaea
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