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… has been doing work in secondary metabolism. The very first CSP I ever worked on back in Brad’s lab, we talked about it … was the Salinispora genome project. And that was a JGI CSP project. They sequenced that genome for us at a time … as many as it did and how that became sort of a trend in genomics. So anyway, yeah, JGI has been working in secondary …

… support researchers exploring how to convert sequence into functional assessments. This is done by synthesizing genes, … and assembling physical DNA constructs that can then be functionally characterized.    We provide custom DNA …

… mechanistic enzymology to natural product biosynthesis to genomics to directed evolution– but it’s just the– it really … Ecopia and collaborators’ landmark genome mining paper: “A genomics-guided approach for discovering and expressing … ATP synthase.” On everninomicin biosynthesis: “EvdS6 is a bifunctional decarboxylase from the everninomicin gene …

… to no genetic tools enabling heterologous expression and functional exploration.  The developed strains represent an …

… the mid-late ’80s. And at that time, you know, it’s before genomics existed. This is before we’re even thinking of … stages of connecting molecules and genes. And then genomics happened. Dan: Yeah, I did my first genome sequence … JGI projects over the years starting with, you know, the CSP that we did and then leading up to today to some …

… and protein folding models, to improve the accuracy of functional predictions and speed up genome analysis. … Phytozome is the JGI's Plant Comparative Genomics portal. Families of related genes representing the …

… Microbiome Data Collaborative (NMDC) to produce open metagenomics data. Taking the JGI’s call for large-scale … of sequence. “We are thrilled to support this year’s CSP awardees as they embark on ambitious projects that span … efforts including systems-based approaches to unravel functional capabilities of plants, microbes and microbial …

… based on feasibility and scientific merit.  Arizona Genomics Institute will produce HMW DNA needed for these …

…  Through this identification, metabolomics enables functional genome annotation, improves understanding of the …

… these researchers will harness capabilities including metagenomics, metatranscriptomics and genome assembly to …