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The Megadata of Lake Mendota - Part 2: Souped Up Computing
… This series is the story of a giant metagenome assembly from Wisconsin’s Lake Mendota. In this episode: a look at the supercomputing that stitches …
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Viruses Reprogram Cells into Different Virocells
… Microbial cells infected by viruses undergo metabolic reprogramming. The … The Ohio State University and the University of Michigan studying how virus infections cause significant metabolic … 1, and 20% to 40% of the microbes are infected at any given time. Microbial viruses can thus have significant impacts on …
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JGI Scientists Pen Genome Watch Articles
… Tanja Woyke and other JGI researchers made their debut writing for the Nature Reviews Microbiology column last year — … characterizing the human microbiome  by its genomes and metagenome , rather than just by 16S ribosomal RNA gene censuses.  Emiley Eloe-Fadrosh ,  Metagenome Program lead, shone a spotlight on  ammonia …
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Boosting Small Molecule Production in Super “Soup”
… Do metabolic pathways from engineered yeasts still work in cell-free environments? … of sustainable chemical products,” said Jewett, one of the study’s senior authors. “But this has been done most … jump in the rate of product formation.” This was the first time CRISPR-Cas9 had been used to modify a cell’s  genome in …
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JGI Accepts 17 Proposals for Community Science Program
… Monitoring Inter-Organism Interactions Within Ecosystems Latest … the University of Massachusetts Amherst and colleagues are studying how chronic warming is altering how microbes … interact with their environment, potentially accelerating soil carbon loss. Orange ribbons mark the heated plots and …
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Rex Malmstrom
… and leader of the Microscale Applications group. Before joining the JGI in 2010, he made the first ever measurements of in situ … Ph.D. in Marine Biology/Biochemistry, University of Delaware BA in … Couradeau, J.S. et al. 2019. Probing the active fraction of soil microbiomes using BONCAT-FACS.  Nature Comm 10(1) 1-10 …
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JGI-UC Merced Interns Share Their 2021 Experiences
… During the summer of 2021, 13 interns from UC Merced spent eight weeks working virtually … new skills needed for their PhD research. And for the first time in this program’s history, two interns returned to … Blurring the Line Between Plasmids and Phages … Evolution of the Mitochondria Internship …
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Better Genome Editing for Bioenergy
… part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a … I will spend the first four sharpening the axe.” In this study,  published in  Metabolic Engineering , a team of … sgRNAs) appeared to be rife with false negatives: that time, the team only found 359 genes to be essential. The …
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Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
… warm-adapted microbes edge polewards, they’d oust resident tiny algae. The cold polar oceans give rise to some of the … algae. But human-induced climate change , a new study suggests, is displacing these important cold-water … of East Anglia (UEA, UK) and senior author of the study. “Prokaryotes are not capable of producing all the …
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Interdisciplinary delegation from the University of Duisburg-Essen explores collaborative opportunities with Lawrence Berkeley National Laboratory
… A two-day kick-off meeting held at Lawrence Berkeley National Laboratory (Berkeley … workshops. Of common interest is the method development to study active sites or single cells in their functional … for mass spectrometry applications, for example, or the timely controlled start of a biochemical reaction which can …
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Trent Northen
… is currently a Senior Staff Scientist at Berkeley Lab. Since joining Berkeley Lab in 2008, Dr. Northen has had leadership … to learn more about the program's areas of focus, major initiatives and more.  … B.S. in Chemical Engineering, University of California Santa …
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JGI Pitches 2022 Visiting Faculty Program Collaborations
… Laboratory (Berkeley Lab) hosted a pitch event promoting fully-supported summer research collaborations through the U.S. Department of Energy (DOE)’s Visiting Faculty Program (VFP) . The VFP is a summer professional … were: Simon Roux and Matthew Kellom for the JGI Metagenome Program Ellen Dow and Elisha Wood-Charlson for …
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