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… for survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and CRAGE … researchers with a powerful addition to their toolkit to study gene function. As a demonstration, the researchers … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science User Facility, …

… Harnessing BER-funded data resources, researchers built an … an interactive browser that allows other researchers to study the genomes and predict the metabolic abilities of … also used the tool to predict possible functions from 733 metagenome-assembled rumen genomes. Finally, they used the …

… By leveraging new tools and large-scale data mining, JGI researchers … Impact This dataset gives researchers a new foundation for studying how fungi produce and manage energy at the cellular … First, they scanned over 26,000 publicly available metagenomes in the JGI's IMG portal for mitochondrial …

… of plant components   The Science There are three main ingredients to tackle when it comes to breaking down a … order to do so is a resource-intensive process. Now, a new study shows how anaerobic fungi — the kind living in the … wasn’t quite accurate, and maybe anaerobic fungi living in soils or the guts of livestock were more capable than …

… bacteria to regulate key components of its reproductive machinery The Science To better understand how beneficial … to have evolved from a parasitic interaction with their soil fungus host, Rhizopus microsporus . Researchers found … reliant on the continued presence of the bacteria. By studying the Rm-Burkholderia symbiosis model, the team was …

… part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a powerful, high-throughput gene-editing tool that can help scientists engineer organisms for … I will spend the first four sharpening the axe.” In this study,  published in  Metabolic Engineering , a team of …

… A new approach for improving functional annotation in fungal genomes. The Science In a proof-of-concept study, researchers demonstrated that a new genetic mapping … species that have been separated for millions of years. The study highlights the genes that could be used to make other …

… Kaushal Sharma, one of five Antioch High School rising juniors who participated in internships at the DOE Joint Genome Institute this summer … his student’s contributions as reviewing close to 3,800 metagenomes to verify geographic locations and assign …

… complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful … attempt to put them back into the original genomes. These metagenome-assembled genomes (MAGs) that came from shotgun … together, they found most bacterial genomes from water and soil communities were at least 80% complete when studied …

… Retracing how the dry rot Serpula lacrymans adapted to a new … rot ( Serpula lacrymans ) is so destructive in houses. A study involving six brown rot fungi reveals the genomic … to sustainable, alternative biofuels and bioproducts. This study lends insights on how the fungus has responded to …

… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more … optimization. Summary Life is all about balance. This study,  recently published in the  Proceedings of the … Foundation, and the JGI Synthesis Program under FP00005685. In addition, M.D. acknowledges funding from a National …

… gas, regulate Earth’s climate. Most methane is produced in environments without oxygen through a process called … confirmation bias, because it enables scientists to study how methanogenesis takes place in the context of the … They could just be switched off.” Yet, after extensive study, Hatzenpicher and his team were able to definitively …