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I-Min (Amy) Chen
… data modeling, and biological data management. She was one of the co-authors and key developers of the … (IMG) family of systems. Before joining LBNL in 2006, she was Director of Application Development Systems at Gene … K, Ratner A, Huang J, Huntemann M, Hajek P, Ritter SJ, Webb C et al. The IMG/M data management and analysis system …
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Dan Rokhsar
Genomics, and led the computational efforts directed towards the sequencing, annotation, and analysis of three … group, and is past lead of the Eukaryotic Genome Program (2010-2019), and JGI Chief Informatics Officer (2013-2016). Dr. Rokhsar joined the faculty of University of …
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The More the Merrier: Making the Case for Plant Pan-genomes
… system traces polyploid genome evolution. Flowering plants abide by the concept, “the more the merrier,” with respect to their genomes. In their base state, they are diploids with two genome copies, one from each parent. Having three …
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Tracking the Origins of Methane-Producing Microbes
… estimated to produce 500 million tons of methane a year, which is over half the total global methane production. They … carbon cycle. All methanogenic archaea use one of three pathways for methanogenesis: hydrogen-dependent and … common); methylotrophic; and, acetoclastic. All three pathways require the gene cluster for methane production known …
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Inspiring STEM Careers Through a Hands-on Everglades Microbiome Study
Journal publication caps JGI pilot project with fledgling Florida high school scientists. The Florida Everglades evokes images of fanboats skimming over swamps, while alligators peer through the waters and clouds of …
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Forming Scientific Connections and Building Community
… through their long standing internship program. In just two months, the students participated in networking workshops, data carpentry hackathons, and also made new …
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Gene Expression: From On-Off Switch to Dial
… library approach to tuning gene expression in metabolic pathways. Compared to the traditional way, which leverages an all-or-nothing approach to … were previously missed in knock-out screens. These results show that this singular library synthesized by JGI was …
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A Shrubbier Version of Rubber
Right now, our natural rubber comes from just one tree species: … that’s native to North America: guayule.  This episode was made in collaboration with our friends at the HudsonAlpha Institute for …
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Zhong Wang
Research in the Analysis R&D group focuses on developing new bioinformatics solutions to support JGI in adopting new genomics technologies, scaling up genomics analysis to … scientists and biostatisticians. Through collaborations with internal and external scientists, the Wang group has …
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You Can Move, But You Can’t Hide
… seek to replicate themselves and spread from cell to cell. Two of the most common forms of MGEs are viruses and … can be found in virtually all of Earth’s ecosystems. A software tool  recently described in  Nature Biotechnology  … their gene content and their genetic sequences. The software was created by researchers under the direction of …
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A Redesign for Yeast’s Genome, Chromosome by Chromosome
… to do more, and understand genomes in general, Jef Boeke, Weimin Zhang (NYU Langone Health) and Leslie Mitchell (Neochromosome) have worked to replace yeast’s native chromosomes with synthetic versions. This project has turned out to be …
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EcoFAB 2025: Advancing Mechanistic Microbial Science Using Fabricated Ecosystems
Book your stay at the conference venue This inaugural event will bring together researchers across major ecosystems and disciplines who are developing and applying laboratory ecosystems to … experimentation of microbiome dynamics. Together, we will explore cutting-edge advancements in constructing, …
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