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An Inside Look at How Plants and Mycorrhizal Fungi Cooperate
A new view into a symbiosis could offer benefits to address climate change: pulling … into a plant’s root cells, and both organisms rearrange their cells around this structure to facilitate sharing.  … This team quantified the expression of over 12,000 fungal genes, in addition to associated plant genes.  All together, …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
In honor of the JGI's 25th anniversary in 2022, we have revisited a … contains about 6% of the human genome . They discovered genes linked to conditions such as cardiovascular disease, … with the HudsonAlpha Institute for Biotechnology. Publications Grimwood, J., Gordon, L., Olsen, A. et al. The …
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2022 Progress Report
Pictured is a timelapse of the Integrative Genomics Building (IGB) seen above is home to … Area are also co-located in the IGB. Vision The vision of the U.S. Department of Energy (DOE) Joint Genome …
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Draft genome sequence of Actinotignum schaalii DSM 15541T: Genetic insights into the lifestyle, cell fitness and virulence
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Model Fern Reveals Insight into DNA Thievery in Ferns
… with C. richardii The Science Fern genomes are huge, and incredibly complex — making it difficult to grasp a deeper understanding of fundamental aspects of fern biology and, more broadly, … stresses, ferns’ secondary metabolites and associated genes are great resources for bioremediation, new …
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Whole metagenome sequencing and 16S rRNA gene amplicon analyses reveal the complex microbiome responsible for the success of enhanced in-situ reductive dechlorination (ERD) of a tetrachloroethene-contaminated Superfund site
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Fungus Fuels Tree Growth
… start pinning down how a fungal symbiont spurs growth of poplar, a potential biofuel feedstock.     The Science … still not well understood — scientists can better fine-tune their engineering efforts of both plants and root … in general; the fungus decreased the expression of poplar genes associated with plant defense (e.g. jasmonic acid and …
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JGI Early Career Researchers Featured in mSystems Special Issue
In a special issue of mSystems , out May 14, 2019, JGI researchers are among the authors who offer perspectives on what the next five years of innovation … in nature. In the last few years, mapping the planet’s viral diversity has advanced drastically, aided by genome …
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Fishing for Novel Cellulose Degraders
… genomic approach to bioprospecting. The Science One of the most vital pieces of equipment for fly fishing is a … ecosystem—particularly those that are in low abundances—and their functional roles in their community. This study shows … caught several microbes from known cellulose-degrading groups, the researchers also hooked and were able to …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the … can deliver multiple types of payloads, such as individual genes, whole pathways, genome-editing tools, and reporters.” … and ecosystem health. But bacteria often fail to express their BGC molecules in the lab. By engineering domesticated …
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JGI on the 2020 Highly Cited Researchers List
… recognized by Clarivate Analytics as “true pioneers in their fields over the last decade, demonstrated by the production of multiple highly-cited papers that rank in the top 1% by … assess and improve the quality of metagenome-assembled viral genomes. The paper appeared in  Nature Biotechnology . …
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DOE JGI Interns Share Their Summer Experiences
… the DOE JGI hosted 10 interns who came from a wide range of backgrounds. Many of them spent the summer crunching … the lab bench, and also do some computational analyses at their desks. As part of the DOE JGI’s efforts to promote … summer, they worked with Zhong Wang’s and Tanja Woyke’s groups, respectively. Each of the interns spoke briefly …
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