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Evolution of a Fungal Gene Expression Regulator
… Describing the largest analysis to date of the modified DNA base 5mC variations in fungi. The … A, C, T or G in a genome sequence can lead to changes in protein structures and functions, but the DNA bases themselves can also be modified. The best-known example of a modified DNA base is a methylation of the …
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Three Join the JGI User Executive Committee
… The JGI User Executive Committee (UEC) recently welcomed three new members earlier this month – Sneha Couvilion of Pacific Northwest National Laboratory, Chris Schadt of Oak Ridge National Laboratory and …
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A One-Stop Shop for Analyzing Algal Genomes
… The PhycoCosm data portal allows anyone to freely investigate the genes of more than 100 … may tune gene expression; and investigate corresponding proteins. PhycoCosm’s built-in connection to the DOE Systems …
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Expanding Horizons with the 2025 JGI-UC Merced Internship Cohort
… contributed to a number of projects, from refining lab protocols at the bench to applying artificial intelligence to aspects … 18 JGI staff. One of the mentors, postdoc Yumary Vasquez, was herself a program alum from the 2022 cohort.  The UC …
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Marchantia Pangenome Highlights Adaptive Nature of Plant Lineages
… ancestral and present-day plants The Science In a recent  Nature Genetics paper , researchers focused on the full … of the model plant  Marchantia polymorpha. Commonly known as liverwort, this was done to gain insights into gene families involved in adaptations seen in later plant lineages. The team found that …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… Meta-omics datasets show that CRISPR-Cas systems determine mutualism or parasitism … This shows that archaea may use CRISPR systems to protect against other, parasitic archaea. However, when  Ca . … was supported in part by the Allen Distinguished Investigator Program, through The Paul G. Allen Frontiers Group, the …
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Data Discovery Tool Helps Identify Microbial Roles within Metagenomes
… Protein annotations provide insights into environmental tendencies The Science The  Metagenome Stability Diagram — a tool within the Integrated Microbial Genomes and Microbiomes … microbes. Researchers can use the tool to correlate protein annotations with ratios of DNA sequence fragments …
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10 From JGI on the 2019 Highly Cited Researchers List
… Clarivate Analytics, formerly the IP & Science arm of Thomson … has released their 2019 list of Highly Cited Researchers , which includes 10 affiliated with the JGI . The 2019 list focused on Highly Cited …
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JGI@25: From Life at the Extremes to Editing Genomes
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and capabilities to enable … in 2018 on the discovery of miniature CRISPR-associated proteins that can target single-stranded DNA. Such proteins …
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Defining a Pan-Genome for Antarctic Archaea
… environments, and researchers are interested in learning how these microbes have learned to adapt from marine to … Antarctic lakes, some of which have salinities 10 times that of seawater. To shed light on the global biogeography in the … This work was supported by the Australian Research Council …
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JGI@25: Expanding Metagenomics to Capture Viral Diversity
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and capabilities to enable … As they infect microbes like bacteria, algae and protists, all kinds of viruses impact many ecological …
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JGI@25: The Little Alga That Could
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and capabilities to enable … within Chlamy, meaning that its RNA can produce up to four proteins, which has far-reaching implications. “This is …
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