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Extracting the Secrets of Secondary Metabolites
… in overcoming this obstacle when it hit the scene in 2019. Now, that power is poised to grow exponentially by … then employ CRISPR in a variety of microbial hosts. Summary Photorhabdus luminescens proves fatal to insects. It is … pairing proved to rapidly confirm enhanced production of 22 metabolites from six biosynthetic gene clusters. One of …
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Model Fern Reveals Insight into DNA Thievery in Ferns
… difficult to grasp a deeper understanding of fundamental aspects of fern biology and, more broadly, land plant … duplication event that occured some 60 million years ago. Massive gene loss, rampant gene duplications, and even more … (Berkeley Lab) took on the Open Green Genome Initiative in 2018 as part of its Community Science Program. The OGG has …
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iPHoP: A Matchmaker for Phages and their Hosts
… pairs to generate a matrix of data points.  Applied to 216,015 high-quality virus sequences in the IMG/VR database, … Research Program awarded under UC-DOE Prime Contract DE-AC02-05CH11231. The work conducted by the U.S. Department of Energy …
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Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… 1) complementation of split luciferase (CSL) and, 2) bioluminescence resonance energy transfer (BRET)-based … databases for homologous YcgR proteins and chose a set of 92 proteins for functional characterization as candidate biosensors. These 92 homologues were synthesized as codon optimized sequences …
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Effects of Polar Light Cycle on Microbial Food Web
… with the seasons. The Science Light-harvesting bacteria (phototrophs) in Antarctica’s Ace Lake defy the norm when it … Antarctic lakes and the nearby Southern Ocean shift from phototrophs to archaea when sunlight becomes scant, Ace … this polar environment. This cycle suggests a reliance on photosynthesis to maintain nutrient cycling that evolved …
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Benjamin Cole
… University of California, San Diego (PhD, 2011) Rensselaer Polytechnic Institute (B.S., 2006) … Selected Publications …
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Pinning Down a Piece of Photosynthesis
… protein, researchers have new insights into how these ocean photosynthesizers cycle carbon in changing conditions. The products of photosynthesis are easy to point out. Plants, algae and … and longtime JGI collaborator Sabeeha Merchant’s group. In 2011, they inventoried a swath of blueprints to find parts …
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Giant Bacteria Found in Guadeloupe Mangroves Challenge Traditional Concepts
… in Complex Systems (LRC) in Menlo Park, Calif. In the June 24, 2022, issue of the journal Science, Volland and colleagues, … it does chemosynthesis, which is a process analogous to photosynthesis for plants.” Another outstanding question is …
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Ian Blaby
… Since 2019 Dr. Blaby heads the Biodesign Platform at the Joint … Laboratory where he focused on functional genomics of phototrophs. Through this and post-doctoral positions at … Anderson et. al., Exploiting algal NADPH oxidase for biophotovoltaic energy. Plant biotechnology journal . 14: 1, …
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Emiley Eloe-Fadrosh
… Dr. Eloe-Fadrosh joined the JGI in 2014 to pursue her research interests in microbial ecology … She stepped into the Metagenome Program Lead position in 2017. She also leads the DOE’s multi-lab National Microbiome Data Collaborative (NMDC). Prospective users with questions on how to partner with the …
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JGI@25: Building a Better Bean
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that …
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The JGI Data Portal: Improving User Experience
… areas of focus and data and computational needs. Over its 23-year history, JGI has produced more than 13 petabytes of …
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