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… A team has optimized a crucial part of CRISPR-Cas9 … tool will make the right cut, researchers created a set of guide RNAs that were effective against 94 percent of the … bp) that directs the endonuclease where to cut, but these “single guide” RNAs (sgRNAs) can be faulty. Without a good …

… DOE user facilities EMSL and JGI announce FY 2020 collaborative FICUS … for User Science (FICUS) program, two Department of Energy (DOE) Office of Science national user … omics and computational resources with JGI’s cutting-edge genomics, DNA synthesis and complementary capabilities. …

… Genomes in a Pan-genomic Context For the study, partly enabled by the JGI’s  Community Science Program , the team … highlighting the fact that the genetic information in a single reference genome is insufficient. “We really have to … said John Vogel, head of the Plant Functional Genomics program at the JGI and a senior author on the …

… Open Green Genomes hits milestone with C. richardii The Science Fern genomes are huge, and incredibly … — making it difficult to grasp a deeper understanding of fundamental aspects of fern biology and, more broadly, … in the land plant tree of life. Ultimately, the resulting comparative framework can inform the efficient production of …

… New genomes highlight the diversity of white rot fungi in the genus Lentinula   The Science … decomposers that can break down all of wood’s components — cellulose, hemicellulose, and the toughest molecule, lignin. … countries. Genome and transcriptome sequencing were enabled by the Community Science Program (CSP) at the U.S. …

… New evidence shows anaerobic fungi can degrade the hardiest of plant components   The Science There are three main … tackle when it comes to breaking down a plant for energy: Cellulose, hemicellulose and lignin, cumulatively called … of the types of chemical bonds in plant cell walls, it enabled researchers to identify specific bond-breakages …