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2022 Progress Report
… Pictured is a timelapse of the Integrative Genomics Building (IGB) seen above is … Area are also co-located in the IGB. Vision The vision of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office …
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Integrating Experimentation with Data
… The JGI and EMSL are U.S. Department of Energy (DOE) Office of Science national scientific user facilities dedicated to … Click to view a downloadable copy of the sponsor prospectus … Keynote Speakers Jim Collins Massachusetts Institute of Technology Kristala Prather Massachusetts Institute of …
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Improving the Cacao Genome and Phytozome
… fungal infections. That’s why Mars, Inc., a maker of chocolate for more than 100 years and one of the world’s largest buyers of cocoa, is collaborating with others to develop healthier … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Boosting Small Molecule Production in Super “Soup”
… still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have … , researchers led by Hal Alper at The University of Texas at Austin and Michael Jewett of Northwestern University describe a two-pronged approach …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the genome. “CRAGE is central to our ability to offer host-engineering for our users,” says JGI Director … used CRAGE to engineer domesticated bacterial strains with novel biosynthetic gene clusters (BGCs). BGCs make diverse …
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Mission
… JGI Mission As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic … the community through responsibly managing our people and resources. Our vision is to lead AI-driven genomic innovation … functions that can address complex challenges in resource resilience and economic growth. The DOE, through its …
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Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
… tiny algae. The cold polar oceans give rise to some of the largest food webs on Earth. And at their base are … is displacing these important cold-water communities of algae with warm-adapted ones, a trend that threatens to … beneficial findings, like antibiotics, pharmaceuticals, and novel enzymes that function at low temperature.” said Katrin …
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Supercomputing, MetaHipMer and the Mega Dataset of Lake Mendota
… before. In 2006, the JGI produced 33 billion base pairs of sequence; by 2023, that number was almost 717 trillion. … to create pipelines, tools and other standardized data resources that the global research community can access and … have been sequenced and assembled through the combined resources of the JGI, NERSC and ExaBiome teams. Part 1: Many, …
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Extracting the Secrets of Secondary Metabolites
… survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … effectiveness has historically been limited due to the lack of robust tools available for carrying CRISPR into … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …
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Supporting Global Research into Actinomycetes
… ActinoBase offers a public portal of insight into special groups of … Prodcast podcast , where she talks about this community resource. ) “Most people study actinomycetes because they … with actinobacteria and serves as a freely accessible resource that taps into a global network of researchers with a …
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Corymbia Genome Expands Terpene Synthesis Knowledge
… Genome annotations of two C. citriodora subspecies broaden understanding of the terpene synthase gene family across eucalypt lineages. The Science From the distinct smell of eucalyptus to the flavor of wine, terpenes are … Sequencing and assembly data carried out by EMBRAPA as part of the  Corymbia  genome project was supported by FAPDF …
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The Megadata of Lake Mendota - Part 1: Many, Many Mers
… Lake Mendota sits right next to the University of Wisconsin, Madison. And Trina McMahon's lab has been sampling the microbes of that lake for over 20 years, to understand how the … giant assembly from Lake Mendota. In this episode: the software evolution that made metagenome assemblies like this …
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