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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… can deliver multiple types of payloads, such as individual genes, whole pathways, genome-editing tools, and reporters.” … enzyme Cas9. Originally, CRAGE was only used to  insert genes of interest. But now, with Cas9, CRAGE can be used for … means that scientists can modify gene expression, or delete genes, all with the rapid engineering capability of CRAGE. …
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Learning to Look
… found in all inoviruses, and then checking the surrounding genes,” he said. “If these genes are similar in size and … San Francisco. Both are co-authors on the study. “By finding a new anti-CRISPR locus, in an inovirus for example, … So anti-CRISPR loci are powerful discovery tools, by finding even one new anti-CRISPR locus, you are unlocking …
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Polar Phytoplankton Need Zinc to Cope with the Cold
… peering into the function and activity of phytoplankton genes and looking at how communities of these microalgae … alga Microglena sp. YARC, which also contains expanded genes for proteins requiring zinc. Co-expression analysis as …
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Effects of Polar Light Cycle on Microbial Food Web
… the natural world. The Impact From the polar regions to the deep ocean, cold environments occupy more space on Earth …
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Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers
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Awakening the Sleeping Carboxylase Function of Enzymes: Engineering the Natural CO2‑Binding Potential of Reductases
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An Automated Tool for Assessing Virus Data Quality
… these sequences may be tainted by the presence of non-viral genes. Up to this point, there has been a lack of fast and … (contigs) of proviruses flanked on one or both sides by genes from the host organism. With the virus-host boundary … methods, it was possible to distinguish between metabolic genes found in the viral genome versus those from the host …
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Introducing New Members of the JGI User Executive Committee
… he said in his candidate statement. “I want to help JGI find a solution to this problem.” He also wants to assist …
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iPHoP: A Matchmaker for Phages and their Hosts
… viruses are merely toolkits. To do anything, they must find a host, and not just any host will do. It must be a …
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Genetic and Functional Diversity Help Explain Pathogenic, Weakly Pathogenic, and Commensal Lifestyles in the Genus Xanthomonas
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How to Submit Sequencing Samples
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JGI@25 RECAP: 2022 Annual Meeting features historical perspectives on JGI’s 25 years
… and what they’re excited about in JGI’s future. Find recordings and recaps of these talks below, starting …
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