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iPHoP: A Matchmaker for Phages and their Hosts
…   To understand virus-host dynamics, computation helps fill in … With metagenomic sequencing, researchers have found more of these viruses than ever before, in all kinds of … to generate a matrix of data points.  Applied to 216,015 high-quality virus sequences in the IMG/VR database, the …
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Extracting the Secrets of Secondary Metabolites
… survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … yield new tools for pest control. Secondary metabolites are highly regulated in bacteria, making it difficult to … and their pathways could fuel further agricultural applications for pest control and understanding how the …
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How Maize Makes An Antibiotic Cocktail
Maize produces a family of compounds that protects it against infections — using … at least 15 zealexins, they suspect there are even more to find. Zealexins are produced in every corn variety and … and environmental interactions, and also have industrial applications, including bioenergy. All plants make …
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Tracing the Evolution of Shiitake Mushrooms
New genomes highlight the diversity of white rot fungi in the genus … fungi are part of the genus Lentinula, which have evolved to decompose hardwoods on every continent besides Europe and …
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How Filamentous Fungi Sense Food
Tracing gene regulatory networks in the model fungus  Neurospora crassa . The Science A team led by researchers at the University of California, Berkeley used a multi-omics approach to … to plant biomass. One of these techniques was DAP-seq, a high-throughput method for identifying protein binding sites …
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JGI@25: Stories from Intern Alumni
… . Over the next few months, we’ll be revisiting a number of notable achievements that showcase our collaborations and capabilities to enable great science that will help solve energy and environmental challenges. Over the past 25 years, the JGI has hosted …
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PhycoCosm Tutorial
… more about PhycoCosm, the largest interactive collection of sequenced algal genomes, omics data and comparative analysis tools developed by the Joint Genome Institute (JGI), a US Department of Energy …
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Toasting to the 2020 JGI-UC Merced Summer Internship Program
On July 30, UC Merced students and their JGI mentors toasted to the end of a nine-week virtual internship. The celebration was … their mentors to ensure projects progressed despite the challenges of remote work. In addition to the knowledge …
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Gene Expression: From On-Off Switch to Dial
… to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of gene … engineering could lead to sustainable pathways for making high-value bioproducts including biofuels. In addition, the … synthesized by JGI was versatile enough for use in multiple applications. This proof-of-concept experiment offers a new …
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Genome Calligrapher: A Web Tool for Refactoring Bacterial Genome Sequences for de Novo DNA Synthesis
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Benjamin Cole
… studying how plants interact with their environment. Prior to joining the Joint Genome Institute, his focus was primarily on how … (scRNA-seq, Spatial Transcriptomics). … University of California, San Diego (PhD, 2011) Rensselaer Polytechnic …
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Meraculous: De Novo Genome Assembly with Short Paired-End Reads
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