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Petra is an affiliate researcher who cultivates marine algae infected by giant viruses from subtropical, …

Cas9 needs guide RNA to lead it to the correct sequence to snip — but not all guides are effective. To … approach: CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, … To do this, they tested each guide in a  Y. lipolytica strain lacking a necessary enzyme for DNA repair. Whereas an …