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… biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth … CRISPR provides researchers with a powerful addition to their toolkit to study gene function. As a demonstration, … the functions of the biosynthetic gene clusters that produce them. The Impact Secondary metabolites are microbial …

… A new approach for improving functional annotation in fungal genomes. The Science In a … across very distant species that no longer mate to produce progeny. The ability to pinpoint which genes underlie … vary in terms of genetics, metabolism and biochemistry. Their capabilities can be harnessed for a wide range of …

… expands inovirus diversity. To answer the question, “Where’s Waldo?” readers need to look for a number of … developed an algorithm that a computer could use to conduct a similar type of search in microbial and metagenomic … without lysing the bacterial host. They can also influence their host’s growth and pathogenicity, in turn affecting the …

… team  announced in  Nature Microbiology an important addition to the synthetic biologist’s toolkit: a technique for  c … versatile engineering system that allows scientists to conduct genome-wide screens and explore biosynthetic pathway. … and ecosystem health. But bacteria often fail to express their BGC molecules in the lab. By engineering domesticated …

… single-cell genomic approach to bioprospecting. The Science One of the most vital pieces of equipment for fly fishing is … ecosystem—particularly those that are in low abundances—and their functional roles in their community. This study shows … the researchers also hooked and were able to reconstruct a high-quality draft co-assembled genome for a new genus …

… Recent study shows eelgrass has been around about 2.5 million years less than previously believed.  The Science … how eelgrass adapted and evolved throughout its history. Their research, published in  August 2023 in  Nature Plants … also shows the younger meadows in the Atlantic ocean are much less diverse than their Pacific Ocean ancestors — …

… stable isotope probing helps ID novel interactions between bacteria and fungi The Science Researchers have successfully automated aspects of a commonly-used process for … microbes who consume the labeled food or water. Later, their DNA can be tested for the isotope, which tells …

… make-up of specific uncultivated microbes from complex environmental samples. The Science A team led by researchers at … microbes, and then efficiently retrieve and characterize their genomes. The Impact Despite great strides in … To overcome this hurdle, a team led by Bernhard Fuchs and his postdoctoral researcher Anissa Grieb at the MPI …

… a microbiome of bacteria, viruses and fungi process carbon and nitrogen, paving the way for future plants and trees … it was possible to identify specific attributes — such as heat resistance, fast growth rates, and an ability to … and growth.  This study builds on the pyrophilous fungi the JGI has previously sequenced , and provides a powerful …

… Through advances in sequencing technologies and computational approaches, more and more virus sequences are being … The microbes that play key roles in cycling nutrients such as carbon, nitrogen and sulfur are themselves regulated by viruses in their environments. Environmental DNA sequencing can help …

… This is the third and final episode of our series on a giant metagenome assembly from Wisconsin’s Lake Mendota. In the last two episodes, we’ve … behind this project. But every part of this project depends on lakewater samples — so this episode is a look at how …