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Fungal Friends or Foes in Plant Roots
Uncovering associations between plant roots and fungi that can help … office building, its roots are akin to the ground floor lobby. People walking into the lobby have many reasons for … . They looked for genes known to be involved in fungal-host interactions and identified 84 gene families that were …
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Plotting a Model for Virus-Host Warfare Deep Below Ground
…   Visualizing a novel, candidate viral genome found in the deep … The battle waged below the Earth’s surface is reconstructed by combining a study of microbial communities (metagenomics) … are using Altiarchaea as a model system to study virus-host interactions. Approximately 150 archaeal viruses had been …
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You Can Move, But You Can’t Hide
… forms of MGEs are viruses and plasmids. They can be found in virtually all of Earth’s ecosystems. A software tool  … and their genetic sequences. The software was created by researchers under the direction of Microbiome Data … into Earth’s ecosystems, researchers must examine the interactions that happen between tiny organisms (microbes) …
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Better Genome Editing for Bioenergy
… part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a … four sharpening the axe.” In this study,  published in  Metabolic Engineering , a team of researchers likewise honed … work? The project was a multi-institutional effort led by then-graduate student Cory Schwartz and his advisor Ian …
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Dan Rokhsar
Dr. Rokhsar joined the DOE Joint Genome Institute in 2000 as the founding … the origin, evolution, and diversity of plants and animals by combining computational genome analysis, sequence-based … IBM Watson Research Center, Yorktown Heights, NY … Publications … 2018 Marthella Foskett Brown Chair, …
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Fungus Fuels Tree Growth
Researchers start pinning down how a fungal symbiont spurs growth of poplar, a … particular interest to the U.S. Department of Energy (DOE). By better understanding how poplar responds to its intimate … publishing  the results in  Molecular Plant-Microbe Interactions . The results were striking. Adding PM193 …
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Daniel Udwary
… serves as a computational biologist for JGI’s Secondary Metabolites group. His research interests lie in use and development of bioinformatics tools … (1996) … List available on Google Scholar … Education … Publications …
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Getting to the Bottom of Fungal Functions Across Earth’s Forests
… between fungal guilds, genes and function. If a tree falls in the forest — whether or not anyone registers the sound — … as the climate warms. However, these are complicated interactions to untangle. Fungi work in cooperation to … of these varied biomes; the forests share only about 20% of their fungal species. To make useful comparisons, the …
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Enlarging Windows into Understanding Gene Functions
JGI innovates protocol revealing how genetic variations in … sequencing or DAP-seq. The technology was developed by Ronan O’Malley , who leads the Sequencing Technologies Group. In an article published November 25, 2021 in Nature Methods , JGI researchers led by co-first …
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2022 Progress Report
Pictured is a timelapse of the Integrative Genomics Building (IGB) seen above is home to the DOE Joint Genome Institute (JGI). Researchers from the DOE Systems …
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JGI@25: Studying Sorghum’s Survival Skills
… reference genome for Sorghum bicolor . Since then, 2,993 publications, 107 patent applications, and 53 patents have … The JGI updates its Sorghum bicolor reference genome and releases it to the community. 2014: GENCODE project begins. … improve the genome’s accuracy, and increase its length by 29.5 Megabasepairs. 2017: Pan-genome analysis of sorghum …
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Taking Stock of the Known and Unknown Microbial Space
… diversity hotspots Over the past few decades, advancements in sequencing technologies have led to an abundance of … cycles. The information gained from understanding the interactions between microbes, hosts, and their environments … of the available datasets. Efforts to recover MAGs by extracting data directly from environmental samples over …
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