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In honor of the JGI's 25th anniversary in 2022, we have … refine and improve the process of finding novel Cas genes and CRISPR systems. The collaboration has resulted in … Prize … Combining forces with UC Berkeley to seek elusive gene-editing proteins … Berkeley Lab coverage … NERSC & JGI …

Do metabolic pathways from engineered yeasts still work in cell-free environments? … (BDO). To do so, the yeasts received fine-tuning of gene expression through genetic rewiring with CRISPR-Cas9 that …

… to summary above^ as well ] The Science The recipe for growing algae as a source of sustainable biofuels seems fairly … stresses, and its transcriptome to learn more about which genes expression patterns. The analysis led to the identification …

Marcel is in charge of several production pipelines (gene calling, functional annotation and methylomics) …

Mini-Metagenomics Approach Helps Identify Novel Archaeal … methanogenic archaea use one of three pathways for methanogenesis: hydrogen-dependent and CO2-reducing, or … and, acetoclastic. All three pathways require the gene cluster for methane production known as Mcr. Until …

The Joint Genome Institute's DNA Synthesis Platform capabilities … into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for bioenergy, … DNA Synthesis platform enables users to validate hypotheses generated from mining genomic data by designing and …

Igor Grigoriev from the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … to terrestrial habitats. The work is part of the JGI’s 1000 Fungal Genomes Project, which aims to provide genomic … with the two publications of the kingdom-wide, multi-gene phylogeny of fungi by James et al. and Sekimoto et al . …

… of plant components   The Science There are three main ingredients to tackle when it comes to breaking down a … JGI data portals and pipelines helped identify potential genes responsible for lignin deconstruction. (The JGI also … conducted RNA sequencing and alignment to the reference fungal  genome . The study’s pivotal NMR (nuclear magnetic …

… their 2019 list of Highly Cited Researchers , which includes 10 affiliated with the JGI . The 2019 list focused … to: Project Manager Kerrie Barry, Cross-Field Category Fungal and Algal Program head Igor Grigoriev , Plant & … Genomics Lead Dan Rokhsar, Molecular Biology & Genetics Staff Data Scientist Asaf Salamov, Plant & Animal …

… for JGI’s Secondary Metabolites group. His research interests lie in use and development of bioinformatics tools for elucidation of biosynthetic gene clusters in bacteria and fungi. Prior to joining the …

… 25th anniversary. Over the last year, we’ve been revisiting a number of notable achievements that showcase our … for anaerobic fungi . Eventually, it’s possible that fungal communities — or enzymes from fungal communities — could pave the way for many different …

Accepted proposals emphasize JGI interests in algae and secondary metabolites. A total of 27 … and then use computational tools to analyze biosynthetic gene clusters and then develop them for a range of … and algae’s roles in nutrient cycling, now a facet of the  Fungal & Algal Program . For example, green algae represent …