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Marine Microbe Contains Multitudes
But SAR324 can be found throughout the water column, from the warm, well-lit surface, to the blue-lit twilight … of SAR324 cells and their gene expression, the team then sequenced community genomes and expressed gene transcripts … data gave the team unprecedented resolution to study the network of genes that contribute to the metabolisms that …
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Uncovering Novel Genomes from Earth’s Microbiomes
… leads to identification of biosynthetic gene clusters for novel secondary metabolites for multiple applications.       … under laboratory conditions, their genomes can’t be sequenced using traditional approaches. Identifying and … repository of 52,515 microbial draft genomes generated from environmental samples around the world, expanding the …
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Exploring novel alkane-degradation pathways in uncultured bacteria from the North Atlantic Ocean
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Microbiome Data Science Team
Molecular Cell 2019) and massive reconstruction of genomes from uncultivated microbes (Nature 2019). Other projects in … of the functional dark matter as well as the development of novel methods to enable large-scale comparative analysis, … al. (2017) Protein structure determination using metagenome sequence data. Science   355(6322):294-298 Paez-Espino D. et …
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Scientific Advisory Committee
… (CSP). A crucial job of the committee is to take the input from the CSP Proposal Study Panel on prioritization of CSP projects and, with concurrence from the DOE Office of Biological and Environmental Research (BER) program, set the final sequence allocation for this program. …
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Secondary Metabolites Program
… interactions with their environments and with each other, from defending against predators to aiding in symbiotic … platforms, tools and data for deciphering regulatory networks, and refining experimental approaches to explore the … computational analyses of BGC size and complexity, BGC sequence composition, metabolic similarity & compatibility, …
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Viral Genomics Group
… and potential biogeochemical impacts of globally abundant ocean viruses.  Nature . 537:689-93. … Selected Publications …
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A Grass Model to Help Improve Giant Miscanthus
Miscanthus  sequence offers insights into benefits of polyploidy and … Center for Biotechnology. Most plants are diploids with two copies of each chromosome, one inherited from each … genes provided by these chromosomes can contribute to novel traits. M. sinensis is a tetraploid, with four sets of …
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DNA Synthesis Program
DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire … Program aims to generate large datasets to explore sequence-function relationships, advancing the discovery of … relationships as well as insights into clade-specific novelties and expansions.  … ICE is an open source registry …
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Mission
…     Our homepage video includes external footage from:  University of Delaware Laura.Selbmann©PNRA. All the … in doing so enabled the JGI to be the first to publish the sequence analysis of the target chromosomes 5, 16, and 19, … basis of their behavior in the environment.  The JGI genome sequences and metabolomes of microbes and microbial …
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A Novel Freshwater to Marine Evolutionary Transition Revealed within Methylophilaceae Bacteria from the Arctic Ocean
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Workforce Development & Education Outreach
… with Biotech Partners to host students transitioning from high school to community college. … University of …
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