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Accelerating Metagenomics Discoveries with Deep Learning
… proteins to become much simpler; instead of aligning sequences with popular, but computationally costly … (And while Mash and BBsketch can be used on nucleotide sequences, they’re not as reliable on amino acid sequences.) Sevim is currently using HMM profiles of protein …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… biological sequences such as biosynthetic gene cluster structures. Zhong Wang, a computational biologist at … Lab’s Computing Sciences Area to develop an efficient metagenome assembler capable of assembling many terabases of … environmental problems,” Wang said. “We are also seeking to work with biotechnology companies including the …
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JGI@25: From Life at the Extremes to Editing Genomes
… CA. Banfield’s observations of the CRISPRs in her microbial sequences piqued Doudna’s interest. As Doudna noted in her … doi: 10.1038/s41467-017-01408-4. Tyson GW et al. Community structure and metabolism through reconstruction of microbial …
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Mining New Frontiers: The Critical Minerals and Materials Joint Call
… — very often they arrive destroyed. Is there any infrastructure to mitigate this problem? …
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Natural Prodcast Episode 18: A CSP Primer
… at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … for you, we sequenced thousands for you or thousands metagenomes. And I think also the quality that we provide. … we also have a lot of analysis pipelines, be it for, again, metagenome, metatranscriptomes for SNP analysis if somebody …
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Natural Prodcast Episode 13: Francisco Barona Goméz
… that you need to do these coordination bonds, then many structures will be able to work. So, for example, in that … of relationship between the natural forces, the chemical structure that is derived from those natural, evolutionary … diversity, because what matters is not a particular structure but the ability of the structure to do something, …
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Natural Prodcast Episode 15: Katherine Duncan
… of natural products from invertebrates, mostly. Dan Udwary: Structure elucidation, yeah. Kate Duncan: Right, yeah, so … there’s been a lot of work on open pond systems and infrastructure and growing microalgae. And to make the biofuels … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the …
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Mining Metagenomes for Cas Proteins
… Institute (JGI), a DOE Office of Science User Facility. The sequences were then biochemically characterized by a team … to foreign genetic elements by incorporating short sequences from infecting viruses and phages. In the event of … the microbes use the genetic information encoded in CRISPR sequences to target the virus and release attack enzymes in …
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Plant Microbial Interactions Group
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Promoting the Power of Viral Metagenomics
… hydrothermal vents – and computationally identifying which sequences represent viruses that were present in the sample. …
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Natural Prodcast Episode 4: Nancy Keller
… they’re complex, they have different tissues, different structures, different spores. I like looking at that I’m a … species”… he’s now found that some fungi have different ITS sequences in their genome, which might get you a little … look at these enzymes and predict, and really place it to structure. There’s still no way to do that.    DAN: Yes. …
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Metabolomics Program
… us to uncover globally distributed molecules with conserved structures, offering fresh insights into DOM's composition. … are able to test hypotheses concerning specific molecular structures involved in DOM cycling. ENVnet can be used in …
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