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… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

… Genomics call is to enable users to perform state-of-the-art functional genomics research and to help them … Biodesign and ‘omics capabilities to enhance understanding of gene and genome function, particularly those not readily achievable … data usage by the applicant/community, and track record of the applicant.  Learn about the general review process or …

… And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … almost never Actinomycetes. And so when we look at their genomes we don’t get the same kind of information that we … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… was really before– or kind of around about when the first genome sequencing was done. But natural products– marine … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …

… to more easily integrate the expertise and capabilities of multiple Department of Energy Office of Science National User Facilities into … provides customized analysis, the JGI also participates in publication of results. … as needed), and the work plan is written into a Statement of Work document. …

… Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … enzymes to do chemical reactions. Obviously, in my work, in genome mining, we have an awful lot of crossover, where us … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh …

… JGI Mission As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic … and manufacturing. Genomic science lies at the heart of biology, providing the foundational knowledge to … information into actionable insights and solutions. Genome-enabled biology provides solutions to strengthen …

… to current problems facing humanity. A major focus are biofuel feedstock species and plant-microbe interactions, … a plant based bioeconomy where plants are a major source of chemical production and contribute to a healthier planet … improve the accuracy of functional predictions and speed up genome analysis. Additionally, the Plant Program is …

… schedule. This should be coming out on the first Thursday of the month, just like I promised. Now I just have to make … exposure to working with Streptomyces, learning more about genome mining, as well as isolation and a little bit of … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain …