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The Science CRISPR-Cas9 is a powerful, high-throughput gene-editing tool that can help scientists engineer organisms for … work? The project was a multi-institutional effort led by then-graduate student Cory Schwartz and his advisor Ian … included researchers at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User …

Menaka Wilhelm, who is the host of JGI’s other podcast, Genome Insider . If you’re a Genome Insider listener, then … Before we start, I realized in listening back to this and editing it that we used a few acronyms that you all might … do the bioinformatics and to synthesize these results into publication? So there’s this really important because we …

The Joint Genome Institute's DNA Synthesis Platform capabilities … convert sequence into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for … or MoClo assemblies … Check out our organism-agnostic CRISPR gRNA design tool  … BOOST provides a suite of tools …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … has been dominated for … well, as long as I can remember, by bacterial research.  So it was great to hear her passion and …

Metabolomics strengthens -omics technologies at the JGI by identifying the actual molecules present in an … this identification, metabolomics enables functional genome annotation, improves understanding of the role small molecules play in diverse biological systems, sheds light on nutrient cycling, and leads to the …

… ‘omics capabilities to enhance understanding of gene and genome function, particularly those not readily achievable … synthesis, metabolomics and analysis will be paid for by the Department of Energy’s funding of the JGI. There is … merit, DOE mission relevance , proposed data usage by the applicant/community, and track record of the …

Facilities into their research. In recognition of the increasingly collaborative and multidisciplinary nature of DOE … synthesis, metabolomics and analysis will be paid for by the Department of Energy’s funding of the JGI. There is … provides customized analysis, the JGI also participates in publication of results. … All proposals undergo technical …

… a method that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and his team  … payloads, such as individual genes, whole pathways, genome-editing tools, and reporters.” JGI-developed genetic …

Nature paper , researchers describe a dataset of microbial genomes sampled from rivers covering 90% of the watersheds … to the community level. The Impact Rivers are transport systems, and their health is heavily reliant on the energy … work across platforms. … This work was partially supported by awards from US Department of Energy (DOE) Office of …

… are abundant and yet exceptionally small, with mini genomes to match. As a result, they cannot process all of … Then, using metagenomes and metatranscriptomes generated by the U.S. Department of Energy (DOE) Joint Genome … systems, the CRISPR-Cas9 system, is a powerful tool in gene editing, but many other systems exist. Investigating the …