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… mining and sequence design with scaling the production of large, difficult to synthesize constructs such as those … engineering pathways to function in heterologous hosts, by combining combinatorial synthesis, high-throughput …

… peril. But corals comprise multiple organisms: a coral host, a photosynthetic microalgae, and a … When warm waters stress corals, it might be their microbes, including their photosynthetic partner, that help …

… Letters of Intent to our Community Science Program Large-Scale Call, as well as successful submissions to our … CSP Large Scale Proposal #1 … CSP Large-Scale LOI #1 … CSP Large-Scale LOI #2 …

… a version of the User Agreement between HHMI, your Host Institution and LBNL is required. NOTE:  If a PI …

… and should generally conform to the guidelines for our  CSP Large Scale call .  Process Proposals may be submitted at … National Laboratory in Oak Ridge, Tennessee: CBI pursues a host of new technologies to alleviate critical cost barriers …

… avenues for using bacteria to produce ethylene and more.  Microbes excel at recycling the abundant miscellanea of … a specific enzyme, Methylthio-alkane Reductase (MAR) in host bacteria Rhodospirillum rubrum . Their work in Nature … we can go beyond that into propanol, propylene, and even larger hydrocarbons that are the staples of our chemical …

… allows us to provide diverse scientific communities with large amounts of standardized high-quality data and …

… particularly sigma factors that initiate transcription in bacteria. Using this technology, which combines an in vitro … expand the known transcriptional regulatory network in bacteria, enabling the discovery of regulatory cascades as … eukaryotes is handled by three distinct RNA polymerases; in bacteria there is only one type of RNA polymerase …

… e ngineering ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly … into the genome. “CRAGE is central to our ability to offer host-engineering for our users,” says JGI Director Nigel … advantage of their joint metabolisms. Because, together, microbes can be used to create compounds more efficiently …

… In the ocean’s North Pacific Subtropical Gyre, microbes tend to stay localized at different depths. But … fluxes in the environment. Moreover, the deep ocean is the largest inorganic reservoir of carbon on earth; because … they drive that high-energy reaction using simple inorganic sulfur-containing chemicals instead of light. Boeuf pointed …