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… DAN: You’re listening to the US. .Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … is an expertise in those two fields and the ability to process samples at scale. So, lots of samples. ALISON: Yeah, … So 10,000. We have many more isolates right now than we’ve processed. So it’s an exercise of going back to the fridge …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … as far as mixed halogenation, di-halogenation. And types of processes that one could imagine biocatalysts being … might you use an enzyme capable of that in an industrial process? Brad: Sure. I mean, I think for those people who …

… technology in order to enhance the quality of single-cell genomes and directly link functional information with … DNA amplification, and sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling … To provide additional functional insights into microbial genomes, the JGI now uses laser microdissection to …

… was really before– or kind of around about when the first genome sequencing was done. But natural products– marine … . And we’ve got new species which we’re currently in the process of almost finished characterizing them. We’ve got … very helpful. So that’s one thing. And it’s a really slow process. And you might not have access to the databases and …

…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national user facility located … The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a high-throughput AI-centric … access to large-scale datasets and analysis tools for genomes, metagenomes, and metabolomics through its data …

… enzymes to do chemical reactions. Obviously, in my work, in genome mining, we have an awful lot of crossover, where us … something that’s promiscuous for it to be useful? Not in a process chemistry route because there, you just need to … want to do. If you’re not looking to develop a commercial process, you can have the ability to build different types …

… almost never Actinomycetes. And so when we look at their genomes we don’t get the same kind of information that we … they always cluster or could the genes be separated on a genome?  Dan: Oh yeah. It’s biology so anything is possible … agar plate we often feed it lots of nutrients and in the process of giving it all these nutrients we make it happy. …