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… was really before– or kind of around about when the first genome sequencing was done. But natural products– marine … . And we’ve got new species which we’re currently in the process of almost finished characterizing them. We’ve got … very helpful. So that’s one thing. And it’s a really slow process. And you might not have access to the databases and …

… technology in order to enhance the quality of single-cell genomes and directly link functional information with … DNA amplification, and sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling … To provide additional functional insights into microbial genomes, the JGI now uses laser microdissection to …

… enzymes to do chemical reactions. Obviously, in my work, in genome mining, we have an awful lot of crossover, where us … something that’s promiscuous for it to be useful? Not in a process chemistry route because there, you just need to … want to do. If you’re not looking to develop a commercial process, you can have the ability to build different types …

And ultimately we went through a whole lot of different processes with plants and animals, really, all over the … tests to see if they’re good, if they can be used. The process of drug discovery, of course, is very complicated, … So, this was when we started saying, we have to have the genomes. We have to look at the full picture of these. And …

… almost never Actinomycetes. And so when we look at their genomes we don’t get the same kind of information that we … they always cluster or could the genes be separated on a genome?  Dan: Oh yeah. It’s biology so anything is possible … agar plate we often feed it lots of nutrients and in the process of giving it all these nutrients we make it happy. …

… to these communities so that it’s not just an extractive process. DAN UDWARY: That’s beautiful. ALISON TAKEMURA: … you decide to tackle a new target or whatever? What’s your process for discovery? CASSANDRA QUAVE: Right, so I think … it’s not that easy. There are still not that many plant genomes, certainly nowhere close to bacterial kinds of …

… recovered and identified from environmental samples (metagenomes). However, the quality and completeness of metagenome-assembled virus sequences vary widely. In a previous … to help researchers assess and improve the quality of metagenome-assembled viral genomes . The Impact The microbes …