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Boosting Small Molecule Production in Super “Soup”
… still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … ways to accelerate bio-design and identifying the best sets of enzymes that enable synthesis of sustainable …
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Defining a Pan-Genome for Antarctic Archaea
… Analysis of haloarchaeal metagenomes broadens understanding of … sequences from six hypersaline lakes, researchers focused on understanding the genomic variation in haloarchaea … Rauer Islands. Additionally, they compared metagenome data generated from samples collected at four Rauer lakes to …
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MGM Workshop at Fisabio Summer School
… June 24-28: Module 2/Microbial Genomics & Metagenomics Workshop The workshop is addressed to students and professionals of biology, biomedical research, the health …
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Metagenomes from Arctic Soil Microbial Communities from the Barrow Environmental Observatory, Utqiaġvik, AK, USA
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Plotting a Model for Virus-Host Warfare Deep Below Ground
… Science Altiarchaea are carbon-fixing microbes and targets of multiple viruses in Earth’s deep subsurface. They are abundant … identified. The JGI researchers surveyed publicly available data in the JGI’s  IMG/M database , information the Probst … 2018, phase 14 project “Development of novel archaeal viruses and the corresponding CRISPR arrays of a highly …
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Gene Expression: From On-Off Switch to Dial
… Scientists have developed a more nuanced library approach to tuning gene expression in metabolic pathways. Compared to … to expression, scientists can now opt for various shades of grey. The ability to fine-tune the level of gene … This novel form of intermediate expression, when used in addition to traditional methods, can offer …
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Exploring Proteomes of Robust Yarrowia lipolytica Isolates Cultivated in Biomass Hydrolysate Reveals Key Processes Impacting Mixed Sugar Utilization, Lipid Accumulation, and Degradation
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JGI announces 2024 Functional Genomics awardees
…   Each year, the JGI accepts proposals for state-of-the-art functional genomics research from reseachers who translate genomic information into biological function. Through our CSP Functional Genomics … Tapping into these functions allows researchers to use them for engineering applications in support of …
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Maureen Berg
… developing new high-resolution and high-throughput methods to link uncultivated viruses to their host. With these new methods, she hopes to expand our understanding of the roles that viruses play in their ecosystems, …
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JGI-Enabled Research Demonstrates the Existence of New Methane-Makers
… is not exclusively for Euryarchaeota. Atmospheric levels of methane, a potent greenhouse gas, regulate Earth’s climate. Most methane is produced … of significant interest for their potential contributions to a sustainable bioeconomy, including, potentially, methane …
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Waiting to Respire
… Genomes from uncultivated bacteria offers clues to ancestral bacteria’s energy sources. More … Communications , two research teams joined forces and data sets to describe bacterial genomes for related … popularizer and communicator (and at one time, the spouse of Lynn Margulis). The information was then used to …
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Boosting Small Molecule Production in Super “Soup”
… Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … ways to accelerate bio-design and identifying the best sets of enzymes that enable synthesis of sustainable …
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