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… part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a … genome with CRISPR-Cas9 in order to interrogate each one’s function. However, the team first needed to fix a defect in … were reliable. In an elegant, quantitative screen, the team designed a pool of sgRNA sequences: six for every gene in …

Chloroplast mimic a platform to capture and utilize carbon in a synthetic fixation cycle. The Science Chloroplasts are … Bordeaux have developed a platform that mimics chloroplast function within a cell-sized system. The Impact Photosynthesis …

Igor Grigoriev from the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … attracted the attention of many mycologists with the two publications of the kingdom-wide, multi-gene phylogeny of … able to resolve the latter question, despite of their well-designed sampling and analysis of their data at the time. …

… diversity of large and giant viruses. While the microbes in a single drop of water could outnumber a small city’s … of 100 times the size of what has typically been associated with viruses, while the genomes of large viruses may be only … Metabolic reprogramming, Schulz explained, makes the host function better under certain conditions, which then helps …

Register here Book your stay at the conference venue This inaugural event will bring together researchers across major … the vision of standardized fabricated ecosystems (EcoFABs) designed for precise manipulation and reproducible … and applying these engineered ecosystems across various biological contexts. The program fosters intimate, dynamic …

Dr. Visel joined the DOE Joint Genome Institute in 2010. As the Deputy … of scientific policy, engaging in interactions with the scientific community at large. … 2021 LBNL … Computational Biology , Nucleic Acids Research . Over 80 publications in peer-reviewed journals including Nature, …

Crete, Greece … Pavlopoulos GA et al. (2023) Unraveling the functional dark matter through global metagenomics. Nature . … Thousands of Small, Novel Genes. Cell. 178(5):1245-1259. Publications on Pubmed | Google Scholar … Thomson Reuters … Human Intestinal Tract ( MetaHIT ); Community Cyber-infrastructure for Advanced Marine Microbial Ecology Research and …

How sex chromosomes “older than dinosaurs” could help improve crop yields.  The Science The fire moss Ceratodon purpureus is a short plant with a complex genome . Now, high-quality reference genome … continue to evolve so rapidly in gene content and structure. He and JGI Plant Program head Jeremy Schmutz …

Scientists find bee gut microbes have a division of labor when it comes … two polysaccharides can yield sugar monomers, it’s only with the aid of specialized bacterial enzymes. Honey bees … Gilliamella,  which mostly resides in the bee’s ileum, a structure analogous to the human small intestine; and  …

… the JGI’s 25th anniversary celebration, the 2022 Annual Meeting featured speakers who shared a look back at the JGI’s … Find recordings and recaps of these talks below, starting with Ari Patrinos. The Genomics Arms Race Ari Patrinos , Former Director of DOE’s Office of Biological and Environmental Research “There are two kinds …

The DOE Joint Genome Institute hosted the hybrid “NeLLi 2023 Symposium” delving into the most recent expansions of … uncovering microbial novelties to deciphering metabolic and functional capabilities. Overview of Symposium Goals …

… our 2024 Community Science Program Annual Call. “It’s exciting to see the diverse portfolio of successful CSP proposals … genomic science projects relevant to the DOE’s Office of Biological and Environmental Research (BER) missions in: … as smaller-scale calls including our New Investigator and Functional Genomics calls, here on our website . See below …