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Extracting the Secrets of Secondary Metabolites
CRAGE-CRISPR combo helps further demystify biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for … Genome Engineering) is a technique researchers can use to integrate large genetic payloads directly into …
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Tanja Woyke Elected to American Academy of Microbiology
Congratulations to the JGI’s Tanja Woyke , who has been elected to the American Academy of Microbiology (AAM) ! She is among the 68 new … Woyke is also one of the organizers for the upcoming Viral EcoGenomics & Applications (VEGA) Symposium which is …
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Evolution of a multi‐step phosphorelay signal transduction system in Ensifer: recruitment of the sigma factor RpoN and a novel enhancer‐binding protein triggers acid‐activated gene expression
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Frederik Schulz
Schulz joined the DOE Joint Genome Institute in 2016 and is leading the New Lineages of Life Group. His research is … ISME Journal LBNL LDRD (Soil Protists) FY2022 LBNL LDRD (Viral Variant Surveillance) FY2021 Austrian Academy of …
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Olpidium, The Key to the Origin of Terrestrial Fungi
Before 2006, Olpidium was one of the many obscure fungi of Chytridiomycota (the … Facility, found that the fungus Olpidium is a link in the evolution and transition of fungi from aquatic to … of British Columbia and Dr. Rochon from Agri-Food Canada at Summerland BC aimed to generate whole genome data …
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Learning to Look
Machine learning approach significantly expands inovirus diversity. To … are important from the standpoint of phage-bacterial coevolution and are also useful tools in CRISPR-Cas …
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Accelerating Metagenomics Discoveries with Deep Learning
On July 6, scientists from Lawrence Berkeley National Laboratory (Berkeley Lab) and other institutions … machines to “learn” features. State of the art algorithms can perform astonishing degrees of feature recognition: for …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
With a new methodology, scientists are now getting more complete genomic results from single … studied with MDA. With the introduction of PTA, JGI users can get more complete single-cell genomes more consistently. …
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Fungus Fuels Tree Growth
Researchers start pinning down how a fungal symbiont spurs … fungus  Mortierella elongata enjoys a dual lifestyle; it can thrive in the soil as a saprophyte, living off decaying … Biology of Tree and Forest Ecosystems (ARBRE) (ANR-11-LABX 0002 01 to F. Martin), JGI Community sequencing program …
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A thermostable Cas9 with increased lifetime in human plasma
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The genome of Polaromonas naphthalenivorans strain CJ2, isolated from coal tar‐contaminated sediment, reveals physiological and metabolic versatility and evolution through extensive horizontal gene transfer
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Duplications and losses of genes encoding known elements of the stress defence system of the Aspergilli contribute to the evolution of these filamentous fungi but do not directly influence their environmental stress tolerance
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