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How Filamentous Fungi Sense Food
… of California, Berkeley used a multi-omics approach to reconstruct and model gene regulatory pathways used by the … which then can be explored in depth for multiple models and their close relatives across the fungal tree of life, … Service Award Trainee Grant 5T32GM007127-39. The work conducted by the US Department of Energy (DOE) Joint Genome …
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The Megadata of Lake Mendota - Part 1: Many, Many Mers
… Lake Mendota sits right next to the University of Wisconsin, Madison. And Trina McMahon's lab has been sampling the microbes … to analyze 500 metagenomes, it was the biggest project the JGI had ever put together.  The next 3 episodes are the …
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Expanding Virophage Diversity
… DNA genomes that co-infect eukaryotic cells along with giant viruses. Virophages are small viruses with … the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science facility, have increased the … 89 contigs were considered to be complete genomes, and their discovery has extended the possible virophage genome …
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Virus-Microbe Interactions of Mud Island Mangroves
… University of Texas at Austin, will defend his dissertation. Some of his research was conducted at the JGI through the DOE Office of Science Graduate … awards graduate students the opportunity to pursue part of their thesis research at one of the DOE national …
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Crops as Tough as World Cup Turf
… need corn, sorghum and other crops to grow well in worse conditions: with more heat, less water and less fertilizer. Grasses do better in these conditions, so plant biologists James Schable, Guangchao Sun …
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Iron-rich Microbial Mats’ Main Players: Marsarchaeota
… Novel archaeal lineage found in Yellowstone may have been important in early Earth conditions. The … (thermophilic) microbes are of interest for their potential use in number of biotechnological … Bill Inskeep of Montana State University has been conducting microbial field studies at Yellowstone, and in this …
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Extracting the Secrets of Secondary Metabolites
… biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth … CRISPR provides researchers with a powerful addition to their toolkit to study gene function. As a demonstration, … the functions of the biosynthetic gene clusters that produce them. The Impact Secondary metabolites are microbial …
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Mapping Heat Resistance in Yeasts
… A new approach for improving functional annotation in fungal genomes. The Science In a … across very distant species that no longer mate to produce progeny. The ability to pinpoint which genes underlie … vary in terms of genetics, metabolism and biochemistry. Their capabilities can be harnessed for a wide range of …
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Learning to Look
… expands inovirus diversity. To answer the question, “Where’s Waldo?” readers need to look for a number of … developed an algorithm that a computer could use to conduct a similar type of search in microbial and metagenomic … without lysing the bacterial host. They can also influence their host’s growth and pathogenicity, in turn affecting the …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… team  announced in  Nature Microbiology an important addition to the synthetic biologist’s toolkit: a technique for  c … versatile engineering system that allows scientists to conduct genome-wide screens and explore biosynthetic pathway. … and ecosystem health. But bacteria often fail to express their BGC molecules in the lab. By engineering domesticated …
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Fishing for Novel Cellulose Degraders
… single-cell genomic approach to bioprospecting. The Science One of the most vital pieces of equipment for fly fishing is … ecosystem—particularly those that are in low abundances—and their functional roles in their community. This study shows … the researchers also hooked and were able to reconstruct a high-quality draft co-assembled genome for a new genus …
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When “The Blob” Made It Hotter Under the Water
… marine heatwave event may foreshadow climate change impact on marine microbial communities. The Science A team of … rise, so do instances of extreme weather events such as hurricanes and droughts. Another one began in late … up and down the water column. They recently shared their findings in Communications Biology . They reported …
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